Trimethylamine N-oxide
Trimethylamine N-oxide (CAS 1184-78-7) is an organonitrogen compound with the formula (CH3)3NO. This colourless solid, with a molecular weight of 75.11 g/mol, functions as a versatile reagent in organic synthesis. It is notably employed as a demetallation and decarbonylation agent for organometallic compounds and facilitates the conversion of thiols to disulfides. Supplied by TSS with a typical assay of 98%.
- IUPAC
- TMANO
- Synonyms
- Trimethylamine-N-oxideTrimethylamine oxideTMAO
Demetallation and Decarbonylation
Trimethylamine N-oxide serves as an effective reagent for the demetallation and decarbonylation of various organometallic compounds, aiding in synthetic transformations.
Thiol Oxidation
This compound mediates the conversion of thiols to disulfides, a valuable reaction in organic chemistry for forming sulfur-sulfur bonds.
Chemical Synthesis
As a synthetic reagent, Trimethylamine N-oxide is utilised in diverse chemical processes, offering specific reactivity for complex molecule construction.
| Molecular weight | 75.11 |
|---|---|
| Linear formula | (CH3)3N(O) |
| Assay | 98% |
| Application | Demetallation1 and decarbonylation2,3 reagent for organometallic compounds. Mediates the conversion of thiols to disulfides.4 |
| Melting point | 220-222 °C(lit.) |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-37/39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Trimethylamine N-oxide used for?
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Trimethylamine N-oxide is primarily used as a demetallation and decarbonylation reagent for organometallic compounds and to mediate the conversion of thiols to disulfides in chemical synthesis.
What is the CAS number and formula for Trimethylamine N-oxide?
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The CAS number for Trimethylamine N-oxide is 1184-78-7, and its linear formula is (CH3)3NO.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Trimethylamine N-oxide with a typical assay of 98%. This product is not represented as USP, BP, EP, or any other pharmacopoeia grade.
How should Trimethylamine N-oxide be handled safely?
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Trimethylamine N-oxide can cause skin irritation (H315), serious eye irritation (H319), and respiratory irritation (H335). Handle with appropriate personal protective equipment including a dust mask (type N95), eyeshields, and gloves. Ensure adequate ventilation.
Does TSS export Trimethylamine N-oxide?
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Yes, Tech Serve Solutions is a global supplier and exporter of fine chemicals, including Trimethylamine N-oxide.
How can I request a quote or sample for Trimethylamine N-oxide?
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To request a quote or sample, please contact our sales team through the website or via direct inquiry, providing your specific requirements.
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