Trimethylacetamide
Trimethylacetamide (CAS: 754-10-9), also known as pivalamide, is a chemical compound with the molecular formula (CH3)3CCONH2 and a molar mass of 101.15 g/mol. This organic amide serves as a valuable building block in chemical synthesis. It is frequently employed in the creation of more complex organic molecules, finding utility across various research and development sectors, including the pharmaceutical and materials science industries. Its structure makes it a useful precursor in organic reactions.
- IUPAC
- Pivalamide
- Synonyms
- Pivalamide

Organic Synthesis Intermediate
Trimethylacetamide is utilised as a key intermediate in the synthesis of various organic compounds. Its amide functionality and tert-butyl group offer specific reactivity for building complex molecular architectures.
Pharmaceutical Research
This compound can serve as a building block in the development of potential pharmaceutical agents. Its structure is amenable to modifications for exploring novel drug candidates.
Materials Science Precursor
In materials science, trimethylacetamide may be used as a precursor or component in the synthesis of novel polymers or functional materials, leveraging its unique structural features.
| Molecular weight | 101.15 |
|---|---|
| Linear formula | (CH3)3CCONH2 |
| Assay | 98% |
| Boiling point | 212 °C(lit.) |
| Melting point | 154-157 °C(lit.) |

Hazard statements
- H302Harmful if swallowed
| Water hazard class (WGK, DE) | 3 |
|---|---|
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Trimethylacetamide used for?
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Trimethylacetamide is used as an intermediate in organic synthesis, a building block in pharmaceutical research, and potentially as a precursor in materials science.
What is the CAS number and chemical formula for Trimethylacetamide?
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The CAS number for Trimethylacetamide is 754-10-9, and its linear formula is (CH3)3CCONH2.
What grade and purity does Tech Serve Solutions supply for Trimethylacetamide?
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Tech Serve Solutions supplies Trimethylacetamide with an assay of 98%. We do not represent this product as USP, BP, or EP grade.
How should Trimethylacetamide be handled safely?
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Trimethylacetamide is classified with the GHS symbol GHS07 and signal word 'Warning'. It carries the hazard statement H302 (Harmful if swallowed). Handle with appropriate personal protective equipment in a well-ventilated area.
Is Trimethylacetamide a controlled substance?
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Based on the provided data, Trimethylacetamide (CAS: 754-10-9) is not indicated as a controlled substance.
How is Trimethylacetamide packed and shipped?
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Tech Serve Solutions, a global supplier and exporter since 1998, ensures that Trimethylacetamide is packed and shipped according to relevant regulations for chemical transport.
How can I request a quote or sample of Trimethylacetamide?
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To request a quote or sample of Trimethylacetamide, please contact our sales team via the website or provide your inquiry details.
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