Trimethoxy(2-phenylethyl)silane
Trimethoxy(2-phenylethyl)silane (CAS: 49539-88-0), with the molecular formula C<sub>6</sub>H<sub>5</sub>CH<sub>2</sub>CH<sub>2</sub>Si(OCH<sub>3</sub>)<sub>3</sub> and a molecular weight of 226.34, is a versatile organosilicon compound. This liquid reagent finds utility in chemical synthesis and materials science, particularly in areas requiring tailored surface modification and the development of advanced materials like nanomaterials and silsesquioxanes.
- IUPAC
- (2-Phenylethyl)trimethoxysilane
- Synonyms
- (2-Phenylethyl)trimethoxysilane

Chemical Synthesis Intermediate
Utilised as a building block in organic and organometallic synthesis, enabling the introduction of the 2-phenylethyl group with a reactive trimethoxysilane functionality.
Materials Science & Nanomaterials
Serves as a precursor for creating hybrid organic-inorganic materials, including POSS nanohybrids and self-assembled monolayers, for surface functionalisation and advanced coatings.
Micro/NanoElectronics Applications
Its properties make it suitable for applications in microelectronics and nanoelectronics, potentially in surface treatments or as a component in deposition processes.
Organosilicon Chemistry
As a trialkoxysilane, it participates in sol-gel processes and hydrolysis/condensation reactions, forming siloxane networks.
| Molecular weight | 226.34 |
|---|---|
| Linear formula | C6H5CH2CH2Si(OCH3)3 |
| Assay | 98% |
| Form | liquid |
| Boiling point | 95-96 °C/2 mmHg(lit.) |
| Density | 1.033 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.475(lit.) |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | Eyeshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 106 °C / 222.8 °F |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Trimethoxy(2-phenylethyl)silane used for?
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Trimethoxy(2-phenylethyl)silane is used in chemical synthesis, materials science, micro/nanoelectronics, and the development of nanomaterials and POSS nanohybrids.
What are the CAS number and formula for Trimethoxy(2-phenylethyl)silane?
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The CAS number is 49539-88-0 and the linear formula is C<sub>6</sub>H<sub>5</sub>CH<sub>2</sub>CH<sub>2</sub>Si(OCH<sub>3</sub>)<sub>3</sub>.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Trimethoxy(2-phenylethyl)silane with an assay of 98%. This product is supplied for research and chemical synthesis purposes and is not represented as USP, BP, or EP grade.
How should Trimethoxy(2-phenylethyl)silane be handled?
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Handle with appropriate personal protective equipment, including eyeshields, gloves, and a suitable respirator, as it may cause skin irritation, eye irritation, and respiratory irritation (H315-H319-H335).
How is Trimethoxy(2-phenylethyl)silane packed and shipped?
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Tech Serve Solutions can export this chemical globally. Packaging details are available upon request for specific orders.
How can I request a quote or sample for Trimethoxy(2-phenylethyl)silane?
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Please contact our sales team directly to request a quote or to inquire about sample availability for Trimethoxy(2-phenylethyl)silane.
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