Triethylenetetramine-N,N,N′,N′′,N′′′,N′′′-hexaacetic acid
Triethylenetetramine-N,N,N′,N′′,N′′′,N′′′-hexaacetic acid (CAS 869-52-3), also known as TTHA, is a chelating agent with the molecular formula [-CH 2N(CH 2CO 2H)CH 2CH 2N(CH 2CO 2H) 2] 2 and a molecular weight of 494.45 g/mol. This polyaminocarboxylic acid is primarily utilised as a complexometric reagent in analytical chemistry, particularly for titrations. Its structure allows it to form stable complexes with various metal ions.
- IUPAC
- TTHA
- Synonyms
- [-CH2N(CH2CO2H)CH2CH2N(CH2CO2H)2]2TTHAN,N,N′,N′′,N′′′,N′′′-hexaacetic acid,869-52-3

Complexometric Titration
TTHA serves as a key reagent in complexometric titrations. It is employed to determine the concentration of metal ions in solution by forming stable, coloured complexes, enabling precise quantitative analysis.
Analytical Chemistry Reagent
As a versatile analytical reagent, TTHA is valuable in various laboratory procedures. Its chelating properties are instrumental in separation techniques and for sequestering metal ions in solution.
Chemical Synthesis
In chemical synthesis, TTHA can function as a building block or a complexing agent. Its functional groups offer possibilities for incorporation into larger molecular structures or for modifying reaction conditions.
| Molecular weight | 494.45 |
|---|---|
| Linear formula | [-CH2N(CH2CO2H)CH2CH2N(CH2CO2H)2]2 |
| Assay | ≥98.0% (T) |
| Grade | purum |
| Melting point | 232-233 °C(lit.) |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
| Ignition residue | ≤0.1% |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Triethylenetetramine-N,N,N′,N′′,N′′′,N′′′-hexaacetic acid used for?
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Triethylenetetramine-N,N,N′,N′′,N′′′,N′′′-hexaacetic acid (TTHA) is primarily used as a complexometric reagent for analytical titrations and in general chemical synthesis. It is effective at forming stable complexes with metal ions.
What are the CAS number and molecular formula for TTHA?
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The CAS number for Triethylenetetramine-N,N,N′,N′′,N′′′,N′′′-hexaacetic acid is 869-52-3. The molecular formula is [-CH 2N(CH 2CO 2H)CH 2CH 2N(CH 2CO 2H) 2] 2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Triethylenetetramine-N,N,N′,N′′,N′′′,N′′′-hexaacetic acid in purum grade with an assay of ≥98.0% (T). We do not represent this product as USP, BP, or EP grade.
How should TTHA be handled safely?
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TTHA (CAS 869-52-3) is classified with Warning signal word and H315, H319, H335 hazard statements, indicating it causes skin irritation, serious eye irritation, and may cause respiratory irritation. Handle with appropriate personal protective equipment, including a dust mask type N95, eyeshields, and gloves, in a well-ventilated area. Avoid breathing dust.
How is TTHA packed and exported?
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TTHA is typically supplied as a powder. As a specialist global supplier and exporter since 1998, Tech Serve Solutions ensures appropriate packaging for safe national and international shipment.
How can I request a quote or sample?
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To request a quote or a sample of Triethylenetetramine-N,N,N′,N′′,N′′′,N′′′-hexaacetic acid, please contact our sales team through the website or by phone. We are pleased to assist with your chemical requirements.
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