Triacsin C from Streptomyces sp.

CAS 76896-80-5C11H17N3OBiochemicals & Reagents

Triacsin C, identified by CAS number 76896-80-5 and chemical formula C11H17N3O, is a potent inhibitor derived from *Streptomyces sp.* with a molecular weight of 207.27 g/mol. It functions by inhibiting acyl-CoA synthetases, thus impacting lipid metabolism pathways. This compound has demonstrated utility in oocyte maturation studies and in investigating cellular processes such as protein palmitoylation and lipid droplet dynamics.

IUPAC: 2,4,7-Undecatrienal nitrosohydrazone,WS1228A

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Triacsin C from Streptomyces sp. (C11H17N3O) — chemical structure, CAS 76896-80-5; Life Science, fine chemical supplied by Tech Serve Solutions

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01 /Applications

Oocyte Maturation Studies

Triacsin C has been utilised to induce maturation in mammalian and amphibian oocytes, offering insights into developmental biology and reproductive processes.

Protein Palmitoylation Research

This compound acts as an inhibitor of palmitoylation, a critical post-translational modification, enabling research into the function of acylated proteins in cellular signaling.

Lipid Metabolism and Droplet Dynamics

Triacsin C aids in stabilising lipid intermediates and influencing the recruitment of proteins like perilipin 3 to the endoplasmic reticulum, facilitating studies on lipid droplet formation and regulation.

02 /Properties

Molecular weight	207.27
Empirical formula	C11H17N3O
Solubility	methanol: soluble4.90 - 5.10 mg/mL, clear (Pale yellow to yellow)methanol: soluble4.90 - 5.10 mg/mL, clear, pale yellow to yellow
Storage temperature	−20°C
Application	Triacsin C was found to induce maturation in mouse and Xenopus oocytes in the absence of long-chain acyl-CoA synthetase. Triacsin C can also block palmitoylation of the G-protein alpha S subunit6. Furthermore, triacsin C can stabilize1-oleoyl-2-acetyl-sn-glycerol (OAG) and enhance perilipin 3 recruitment to the endoplasmic reticulum (ER) in mouse cells7.

03 /Identifiers & registry

CAS number

76896-80-5

MDL number

MFCD00798237

PubChem substance

24900214

04 /Additional specifications

Shipped In	wet ice

05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is Triacsin C used for?

Triacsin C is primarily used in research as an inhibitor of acyl-CoA synthetases, impacting lipid metabolism, protein palmitoylation, and oocyte maturation.

What is the CAS number and formula for Triacsin C?

The CAS number for Triacsin C is 76896-80-5, and its chemical formula is C11H17N3O.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies Triacsin C at research grade. TSS does not represent this product as USP, BP, EP, or for use in pharmaceutical, nutraceutical, or food applications.

What are the safety and handling considerations for Triacsin C?

Triacsin C is classified with a WGK Germany rating of 3, indicating it is hazardous to water. Handle with appropriate personal protective equipment in a well-ventilated area. Consult the Safety Data Sheet for detailed information.