Trazodone hydrochloride
Trazodone hydrochloride (CAS 25332-39-2), with the molecular formula C19H22ClN5O · HCl and a molecular weight of 408.32 g/mol, is a complex organic compound. It is recognised for its role as a bioactive small molecule and an inhibitor of biogenic amine transport. Supplied by Tech Serve Solutions, this compound is primarily utilized in research settings within cell biology, neuroscience, and as a tool for studying GPCR modulators.
- IUPAC
- 2-[3-[4-(3-Chlorophenyl)-1-piperazinyl]propyl]-1,2,4-triazolo[4,3-a]pyridin-3(2H)-one hydrochloride

Neuroscience Research
Trazodone hydrochloride is employed in neuroscience research to investigate pathways related to mood disorders and sleep regulation, owing to its known interactions with serotonin receptors.
Cell Signaling Studies
This compound serves as a valuable tool in cell signaling research, particularly for studies involving GPCRs and their modulatory effects on cellular responses.
Drug Discovery and Development
As an approved therapeutic/drug candidate, Trazodone hydrochloride is used in preclinical research for the development of new pharmaceutical agents targeting neurological conditions.
Biochemical Reagent
It functions as a biochemical reagent in various laboratory assays and experiments, contributing to the understanding of biological mechanisms at a molecular level.
| Molecular weight | 408.32 |
|---|---|
| Empirical formula | C19H22ClN5O · HCl |
| Assay | ≥99% (HPLC) |
| Form | powder |
| Solubility | 45% (w/v) aq 2-hydroxypropyl-β-cyclodextrin: soluble23.3 mg/mLmethanol: soluble25 mg/mL, clear, colorless0.1 M HCl: soluble7.4 mg/mLDMSO: solubleH2O: soluble, hazy, colorless |


Hazard statements
- H302Harmful if swallowed
- H351Suspected of causing cancer
Precautionary statements
- P281Use personal protective equipment as required
| Protective equipment | Eyeshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22-40 |
| Safety statements (S) | 22-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Gene Information | human ... HTR1A(3350), HTR1B(3351), HTR1D(3352), HTR1E(3354), HTR1F(3355), HTR2C(3358) |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Trazodone hydrochloride used for?
+
Trazodone hydrochloride is used in research settings, particularly in neuroscience and cell biology, for studying its effects on biogenic amine transport and GPCR modulation.
What are the CAS number and formula for Trazodone hydrochloride?
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The CAS number for Trazodone hydrochloride is 25332-39-2, and its empirical formula is C19H22ClN5O · HCl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Trazodone hydrochloride with a purity of ≥99% (HPLC). This is a research-grade chemical and is not supplied as USP, BP, EP, or pharmacopoeia grade.
What are the safety considerations when handling Trazodone hydrochloride?
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Trazodone hydrochloride is classified with GHS07 and GHS08 symbols and a 'Warning' signal word. It carries hazard statements H302 (Harmful if swallowed) and H351 (Suspected of causing cancer). Appropriate personal protective equipment, including eyeshields, gloves, and respiratory protection (type N100 or P3 filters), must be used. Handle with caution, avoiding dust formation and ingestion. P281: Use personal protective equipment as required.
Is Trazodone hydrochloride shipped internationally?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including Trazodone hydrochloride.
How can I request a sample or quote for Trazodone hydrochloride?
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To request a sample or a quote for Trazodone hydrochloride, please contact our sales team via the website or direct email, providing your specific requirements.
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