Tranilast
Tranilast (CAS: 53902-12-8, Formula: C18H17NO5, Molar Mass: 327.33 g/mol) is a bioactive small molecule supplied by Tech Serve Solutions. It is an anthranilic acid derivative known for its anti-allergic and anti-inflammatory properties. Tranilast is primarily utilised in research settings to investigate its effects on cellular processes, particularly related to mast cell function and the arachidonic acid cascade. It is supplied as a white to beige powder.
- IUPAC
- 2-[[3-(3,4-Dimethoxyphenyl)-1-oxo-2-propenyl]amino] benzoic acid,3,4-DAA,N-(3,4-Dimethoxycinnamoyl)anthranilic acid,Rizaben,SB-252218
- Synonyms
- 3,4-DAAN-(3,4-Dimethoxycinnamoyl)anthranilic acidRizabenSB-252218
Research into Mast Cell Function
Tranilast has been studied for its effects on mast cell surface receptors in murine bone marrow-derived mast cells. This research contributes to understanding allergic responses and inflammatory pathways.
Investigation of Arachidonic Acid Cascade
As a compound related to the arachidonic acid cascade, Tranilast is employed in biochemical research to explore its role in mediating cellular signaling pathways associated with inflammation.
Bioactive Small Molecule Studies
Tranilast serves as a valuable tool in cell biology and cell signaling research due to its known biological activity. It is used to investigate cellular responses and potential therapeutic targets.
| Molecular weight | 327.33 |
|---|---|
| Empirical formula | C18H17NO5 |
| Assay | ≥98% (HPLC) |
| Form | powder |
| Colour | white to beige |
| Solubility | DMSO: >10 mg/mLH2O: insoluble |
| Storage temperature | 2-8°C |
| Melting point | 166.2-168.2 °C(lit.) |
| Application | The effect of Tranilast on mast cell surface receptors was studied in murine bone marrow-derived mast cells.1 |
Hazard statements
- H302Harmful if swallowed
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Gene Information | human ... VEGFA(7422), VEGFB(7423), VEGFC(7424) |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Tranilast used for?
+
Tranilast is used in research, particularly for studying mast cell function and the arachidonic acid cascade, and is classified as a bioactive small molecule and an approved therapeutic/drug candidate.
What is the CAS number and formula for Tranilast?
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The CAS number for Tranilast is 53902-12-8 and its empirical formula (Hill notation) is C18H17NO5.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Tranilast with an assay of ≥98% (HPLC). This product is intended for research and laboratory use. TSS does not represent this product as USP, BP, EP, or pharmaceutical grade.
What are the safety and handling recommendations for Tranilast?
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Tranilast is classified with GHS07 symbol and a 'Warning' signal word, with hazard statement H302 (Harmful if swallowed). Recommended personal protective equipment includes a dust mask type N95 (US), eyeshields, and gloves. Handle with appropriate caution.
How is Tranilast shipped and exported?
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Tranilast is stored at 2-8°C. As a global supplier, Tech Serve Solutions exports chemicals worldwide, adhering to all relevant shipping and customs regulations.
How can I request a quote or sample for Tranilast?
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To request a quote or a sample of Tranilast, please contact the Tech Serve Solutions sales team through our website or by phone.
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