Trandolapril

CAS 87679-37-6C24H34N2O5Cell Biology

Trandolapril (CAS 87679-37-6), with the molecular formula C24H34N2O5 and a molecular weight of 430.54 g/mol, is a white powder. It functions as an angiotensin-converting enzyme (ACE) inhibitor, widely recognised for its role in cardiovascular therapeutics. This compound is primarily utilised in the research and development of treatments for hypertension and heart failure, owing to its specific mechanism of action in regulating blood pressure.

IUPAC: (2S,3aR,7aS)-1-[(2S)-2-[[(1S)-1-(ethoxycarbonyl)-3-phenylpropyl]amino]-1-oxopropyl]octahydro-1H-Indole-2-carboxylic acid,Mavik

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Trandolapril (C24H34N2O5) — chemical structure, CAS 87679-37-6; Life Science, fine chemical supplied by Tech Serve Solutions

AbbottAngiotensin MetabolismBioactive Small MoleculesCell BiologyEnzyme InhibitorsNeuropeptidesNeuroscienceNeurotransmissionNeurotransmitter MetabolismPeptides and Proteins

01 /Applications

ACE Inhibitor Research

Trandolapril is employed in research settings to study the mechanisms of the renin-angiotensin-aldosterone system. Its potent inhibitory activity on angiotensin-converting enzyme makes it a valuable tool for investigating pathways related to blood pressure regulation and cardiovascular disease.

Hypertension Treatment Development

As an established ACE inhibitor, Trandolapril serves as a reference compound and a potential lead in the development of novel therapeutics for managing hypertension. Its efficacy in clinical settings informs ongoing research into cardiovascular pharmacotherapy.

Heart Failure Research

The compound is utilised in studies investigating the role of ACE inhibition in the management of heart failure. Its capacity to reduce afterload and preload contributes to understanding treatment strategies for patients with compromised cardiac function.

02 /Properties

Molecular weight	430.54
Empirical formula	C24H34N2O5
Assay	≥98% (HPLC)
Form	white powder
Solubility	DMSO: ≥20 mg/mL
Storage temperature	room temp

03 /Safety & handling

Protective equipment	Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Water hazard class (WGK, DE)	3

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

87679-37-6

05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is Trandolapril used for?

Trandolapril is primarily used in the research and development of treatments for hypertension and heart failure due to its action as an angiotensin-converting enzyme (ACE) inhibitor.

What are the CAS number and formula for Trandolapril?

The CAS number for Trandolapril is 87679-37-6, and its molecular formula is C24H34N2O5.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies Trandolapril with a purity of ≥98% (HPLC). We do not represent this product as USP, BP, or EP grade unless explicitly stated in the product specifications.

What safety precautions should be taken when handling Trandolapril?

When handling Trandolapril, it is essential to use safety equipment including eyeshields, gloves, and a type N95 (US) or type P1 (EN143) respirator filter. The compound is classified with WGK Germany 3, indicating a high hazard to water.

How is Trandolapril packed, shipped, and exported?

Trandolapril is typically supplied as a white powder and is stored at room temperature. Tech Serve Solutions is a global supplier and exporter of fine chemicals, pharmaceutical intermediates, and laboratory reagents.