Tetrahydro-4H-pyran-4-one
Tetrahydro-4H-pyran-4-one (CAS: 29943-42-8), a cyclic ketone with the formula C5H8O2, presents as a valuable building block in organic synthesis. Its molecular weight is 100.12 g/mol. This versatile compound finds application in the construction of more complex molecular architectures, particularly within the fields of heterocyclic chemistry and pharmaceutical intermediate development. It is supplied by Tech Serve Solutions with a minimum assay of 99%.
- IUPAC
- 4-Oxotetrahydropyran
- Synonyms
- 4-Oxotetrahydropyran

Heterocyclic Synthesis
Tetrahydro-4H-pyran-4-one serves as a key intermediate for synthesizing various substituted pyrans and other heterocyclic systems. Its ketone functionality allows for diverse chemical transformations.
Pharmaceutical Intermediates
This compound is utilised in the multi-step synthesis of active pharmaceutical ingredients (APIs) and drug candidates. Its structure is amenable to modifications for creating novel therapeutic agents.
Organic Building Block
As a functionalized cyclic molecule, it is employed in academic and industrial research for developing new synthetic methodologies and creating diverse chemical libraries.
| Molecular weight | 100.12 |
|---|---|
| Empirical formula | C5H8O2 |
| Assay | 99% |
| Boiling point | 166-166.5 °C(lit.) |
| Density | 1.084 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.452(lit.) |

Hazard statements
- H226Flammable liquid and vapour
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 55 °C / 131 °F |
| Transport (UN / ADR) | UN 1224C 3 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Risk statements (R) | 10 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Tetrahydro-4H-pyran-4-one used for?
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Tetrahydro-4H-pyran-4-one is primarily used as a building block in organic synthesis, particularly for creating heterocyclic compounds and pharmaceutical intermediates. Its ketone functionality allows for a range of chemical reactions.
What is the CAS number and formula for Tetrahydro-4H-pyran-4-one?
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The CAS number is 29943-42-8, and its empirical formula is C5H8O2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Tetrahydro-4H-pyran-4-one with a minimum assay of 99%. This product is intended for research and chemical synthesis purposes; TSS does not represent it as USP, BP, or EP grade.
How should Tetrahydro-4H-pyran-4-one be handled safely?
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Tetrahydro-4H-pyran-4-one is a flammable liquid and vapour (H226). Handle with appropriate personal protective equipment, including safety goggles, gloves, and respiratory protection, in a well-ventilated area, away from ignition sources.
How is Tetrahydro-4H-pyran-4-one shipped by Tech Serve Solutions?
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This chemical is classified under UN 1224C, Class 3, Packing Group III, indicating it is shipped as a flammable liquid according to international transport regulations.
How can I request a quote or sample for Tetrahydro-4H-pyran-4-one?
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To request a quote or sample, please contact our sales department through the website or by phone, providing your specific requirements and contact information.
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