4-Phenylmorpholine
4-Phenylmorpholine (CAS 92-53-5), a chemical compound with the formula C10H13NO and a molecular weight of 163.22 g/mol, is a valuable heterocyclic building block. It is primarily utilised in chemical synthesis and research laboratories. Its properties make it suitable for use as an internal standard in analytical techniques such as gas chromatography, particularly for the determination of alkaloids. Tech Serve Solutions supplies this compound with an assay of 98%.

Internal Standard in Gas Chromatography
4-Phenylmorpholine serves as an effective internal standard for the gas chromatographic determination of alkaloids. Its stability and distinct chromatographic behaviour aid in accurate quantification.
Chemical Synthesis Intermediate
As a morpholine derivative, 4-Phenylmorpholine functions as a versatile building block in organic synthesis. It is incorporated into more complex molecular structures within research and development settings.
Research and Development
This compound is employed in various laboratory research applications, contributing to the exploration of new chemical entities and synthetic pathways.
| Molecular weight | 163.22 |
|---|---|
| Empirical formula | C10H13NO |
| Assay | ≥98% |
| Boiling point | 165-170 °C/45 mmHg(lit.) |
| Vapour pressure | <0.1 mmHg (20 °C) |
| Vapour density | 5.63 (vs air) |
| Application | 4-Phenylmorpholine was used as internal standard during the determination of alkaloids by gas chromatographic method1. |
| Melting point | 51-54 °C(lit.) |

Hazard statements
- H302Harmful if swallowed
- H311Toxic in contact with skin
- H319Causes serious eye irritation
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P312Call a POISON CENTER if you feel unwell
| Protective equipment | Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges |
|---|---|
| Flash point | 113 °C / 235.4 °F |
| Transport (UN / ADR) | UN 2811 6.1 / PGIII |
| Water hazard class (WGK, DE) | 2 |
| Hazard codes (EU) | T |
| Risk statements (R) | 22-24 |
| Safety statements (S) | 36/37-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-Phenylmorpholine used for?
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4-Phenylmorpholine is used as an internal standard in gas chromatography for alkaloid determination and as a building block in chemical synthesis and research.
What are the CAS number and formula for 4-Phenylmorpholine?
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The CAS number for 4-Phenylmorpholine is 92-53-5, and its molecular formula is C10H13NO.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 4-Phenylmorpholine with an assay of 98%. We do not represent this product as USP, BP, EP, or any other pharmacopoeia grade.
How should 4-Phenylmorpholine be handled safely?
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4-Phenylmorpholine is a dangerous substance. It is harmful if swallowed, toxic in contact with skin, and causes serious eye irritation. Appropriate personal protective equipment, including eyeshields, face shields, gloves, and P2 respirator cartridges, should be used. Handle in a well-ventilated area. In case of contact or ingestion, seek immediate medical attention.
Is 4-Phenylmorpholine a controlled substance?
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The provided data does not indicate that 4-Phenylmorpholine is a controlled substance.
How is 4-Phenylmorpholine packed and shipped?
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4-Phenylmorpholine is shipped as UN 2811, Class 6.1 (Toxic substances), Packing Group III. Packaging is designed to ensure safe transport and compliance with international shipping regulations.
How can I request a quote or sample?
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To request a quote or sample of 4-Phenylmorpholine, please contact our sales team through the website or by phone. Please specify the quantity required.
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