Tetrafluorosuccinic anhydride
Tetrafluorosuccinic anhydride (CAS: 699-30-9, C4F4O3) is a fluorinated organic compound with a molecular weight of 172.03 g/mol. As a highly reactive carboxylic acid anhydride, it serves as a valuable building block in organic synthesis. Its fluorinated nature makes it particularly useful for introducing trifluoromethyl or related functional groups into complex molecules, finding applications in the development of new materials and pharmaceuticals.
- IUPAC
- Perfluorosuccinic anhydride

Fluorinated Building Block
Tetrafluorosuccinic anhydride is utilised as a key synthon for the preparation of various fluorinated organic compounds. It enables the incorporation of fluorinated moieties into larger molecular structures, which is crucial in medicinal chemistry and materials science.
Synthesis of Heterocycles
This compound can be employed in the synthesis of fluorinated heterocyclic compounds. These heterocycles are of significant interest for their potential biological activities and unique material properties.
Reagent in Organic Synthesis
Its anhydride functionality allows for reactions with nucleophiles, making it a versatile reagent for derivatisation and functional group transformations in advanced chemical research.
| Molecular weight | 172.03 |
|---|---|
| Empirical formula | C4F4O3 |
| Assay | ≥98.0% (T) |
| Boiling point | 54-56 °C(lit.) |
| Density | 1.609 g/mL at 20 °C(lit.) |
| Refractive index | n20/D 1.327 |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H331Toxic if inhaled
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
- P311Call a POISON CENTER or doctor
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US) |
|---|---|
| Transport (UN / ADR) | UN 2810 6.1 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | T |
| Risk statements (R) | 23-36/37/38 |
| Safety statements (S) | 26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Tetrafluorosuccinic anhydride used for?
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Tetrafluorosuccinic anhydride is used as a fluorinated building block in organic synthesis, particularly for creating fluorinated organic compounds and heterocycles. It is also a reagent for derivatisation and functional group transformations.
What are the CAS number and formula for Tetrafluorosuccinic anhydride?
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The CAS number for Tetrafluorosuccinic anhydride is 699-30-9 and its chemical formula is C4F4O3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Tetrafluorosuccinic anhydride with an assay of ≥98.0% (T). TSS does not represent this product as USP, BP, EP, or any other pharmacopoeia grade unless explicitly stated.
How should Tetrafluorosuccinic anhydride be handled safely?
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Tetrafluorosuccinic anhydride is a danger substance; it causes skin irritation (H315), serious eye irritation (H319), and respiratory irritation (H335). It is also toxic if inhaled (H331). Handle with appropriate personal protective equipment including eyeshields, faceshields, gloves, and a suitable respirator. Ensure adequate ventilation.
Is Tetrafluorosuccinic anhydride a controlled substance?
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The provided data does not indicate that Tetrafluorosuccinic anhydride is a controlled substance.
How is Tetrafluorosuccinic anhydride packed, shipped, and exported?
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Tetrafluorosuccinic anhydride is shipped as UN 2810, Hazard Class 6.1, Packing Group II. For specific packaging and export details, please contact our sales team.
How can I request a quote or sample for Tetrafluorosuccinic anhydride?
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To request a quote or a sample of Tetrafluorosuccinic anhydride, please visit the product page on the Tech Serve Solutions website and use the designated 'Request Quote' or 'Request Sample' functions.
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