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Tetrafluoroisophthalonitrile

CAS 2377-81-3C6F4-1Chemical Synthesis

Tetrafluoroisophthalonitrile (CAS: 2377-81-3) is a chemical compound with the molecular formula C6F4-1,3-(CN)2 and a molecular weight of 200.09 g/mol. This organic building block, featuring a fluorinated benzene ring substituted with two nitrile groups, is primarily utilised in chemical synthesis. Its specific structure makes it a valuable intermediate for creating more complex molecules within research and development settings, particularly in the fields requiring specialised fluorinated or nitrile-containing compounds.

Synonyms
3,5-Dicyanotetrafluorobenzene1,3-Dicyanotetrafluorobenzene1,3-Dicyano-2,4,5,6-tetrafluorobenzene
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Tetrafluoroisophthalonitrile (C6F4-1) — chemical structure, CAS 2377-81-3; Chemistry, fine chemical supplied by Tech Serve Solutions
Building BlocksC8 to C9Chemical SynthesisCyanides/NitrilesNitrogen Compounds
01 /Applications

Organic Synthesis Intermediate

Tetrafluoroisophthalonitrile serves as a key intermediate in the synthesis of complex organic molecules. Its unique combination of fluorine atoms and nitrile functionalities allows for diverse chemical transformations.

Fluorinated Compound Development

The presence of four fluorine atoms makes this compound useful for introducing fluorinated moieties into novel materials and molecules, which can impart specific properties such as increased stability or altered electronic characteristics.

Nitrile Chemistry

As a dinitrile, it can participate in reactions characteristic of nitriles, including hydrolysis, reduction, or cycloaddition, leading to a variety of nitrogen-containing heterocycles or functionalised derivatives.

02 /Properties
Molecular weight200.09
Linear formulaC6F4-1,3-(CN)2
Assay98%
Melting point78-79 °C(lit.)
03 /Safety & handling
GHS hazard pictogram: Harmful / irritant (GHS07)
Harmful / irritant
Warning

Hazard statements

  • H302Harmful if swallowed
  • H312Harmful in contact with skin
  • H315Causes skin irritation
  • H319Causes serious eye irritation
  • H332Harmful if inhaled
  • H335May cause respiratory irritation

Precautionary statements

  • P261Avoid breathing dust, fume, gas or vapours
  • P280Wear protective gloves, clothing and eye/face protection
  • P305IF IN EYES
Protective equipmentdust mask type N95 (US), Eyeshields, Gloves
Water hazard class (WGK, DE)3
Hazard codes (EU)Xn
Risk statements (R)20/21/22-36/37/38
Safety statements (S)26-37/39

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry
CAS number
2377-81-3
MDL number
MFCD00013290
PubChem substance
24859652
05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is Tetrafluoroisophthalonitrile used for?

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Tetrafluoroisophthalonitrile is used as a versatile building block and intermediate in organic synthesis, particularly for the creation of complex fluorinated and nitrile-containing compounds for research and development.

What are the CAS number and molecular formula of Tetrafluoroisophthalonitrile?

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The CAS number is 2377-81-3 and the molecular formula is C6F4-1,3-(CN)2.

What grade and purity does Tech Serve Solutions supply?

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Tech Serve Solutions supplies Tetrafluoroisophthalonitrile with an assay of 98%. This is typically considered a technical or research grade, and we do not represent it as USP, BP, or EP.

How should Tetrafluoroisophthalonitrile be handled safely?

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Tetrafluoroisophthalonitrile is classified as harmful if swallowed, in contact with skin, or if inhaled, and causes skin and serious eye irritation, as well as respiratory irritation. Handle with appropriate personal protective equipment including Eyeshields, Gloves, and a dust mask type N95 (US). Ensure good ventilation.

How is Tetrafluoroisophthalonitrile packed and shipped?

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Tetrafluoroisophthalonitrile is carefully packed according to industry standards to ensure safe transit and is exported globally by Tech Serve Solutions.

How can I request a quote or sample?

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To request a quote or a sample of Tetrafluoroisophthalonitrile, please contact our sales team through the website or by phone.

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