Tetrafluoro-2-(tetrafluoro-2-iodoethoxy)ethanesulfonyl fluoride
Tetrafluoro-2-(tetrafluoro-2-iodoethoxy)ethanesulfonyl fluoride (CAS: 66137-74-4), with the molecular formula ICF2CF2OCF2CF2SO2F and a molecular weight of 426.00, is a specialised fluorinated organic building block. Its unique structure, featuring both an iodoethoxy and a sulfonyl fluoride moiety, makes it a valuable reagent in advanced chemical synthesis. It serves as a versatile intermediate for introducing fluorinated segments into larger molecules.

Fluorinated Organic Synthesis
This compound is employed as a building block in the synthesis of complex fluorinated organic molecules. The presence of the iodine atom and the sulfonyl fluoride group allows for diverse chemical transformations.
Materials Science
It can be utilised in the development of novel fluorinated materials with specific properties, such as polymers or surface coatings, where its unique functional groups can impart desired characteristics.
Pharmaceutical and Agrochemical Intermediates
The introduction of fluorinated groups is a common strategy in drug discovery and crop protection. This compound can serve as an intermediate in the synthesis of new active pharmaceutical ingredients (APIs) or agrochemicals.
| Molecular weight | 426.00 |
|---|---|
| Linear formula | ICF2CF2OCF2CF2SO2F |
| Assay | 97% |
| Boiling point | 127 °C(lit.) |
| Density | 2.051 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.35(lit.) |

Hazard statements
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 113 °C / 235.4 °F |
| Transport (UN / ADR) | UN 3265 8 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 34 |
| Safety statements (S) | 26-27-28-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Tetrafluoro-2-(tetrafluoro-2-iodoethoxy)ethanesulfonyl fluoride used for?
+
Tetrafluoro-2-(tetrafluoro-2-iodoethoxy)ethanesulfonyl fluoride is primarily used as a fluorinated building block in organic synthesis for creating complex fluorinated molecules, materials, and potential pharmaceutical or agrochemical intermediates.
What are the CAS number and chemical formula?
+
The CAS number is 66137-74-4 and the chemical formula is ICF2CF2OCF2CF2SO2F.
What grade and purity does Tech Serve Solutions supply?
+
Tech Serve Solutions supplies this product with a minimum assay of 97%. This is a research or technical grade chemical, and TSS does not represent it as USP, BP, or EP grade.
How should this chemical be handled safely?
+
This compound is classified as corrosive (H314) and causes severe skin burns and eye damage. Handle with extreme caution, wearing appropriate personal protective equipment including face shields, gloves, goggles, and suitable respiratory protection (e.g., type ABEK respirator filter).
How is this product packed, shipped, and exported?
+
As per UN 3265, 8 / PGII regulations, this product is packed and shipped as a corrosive liquid, suitable for international export by Tech Serve Solutions.
How can I request a sample or quote?
+
To request a sample or a quote, please contact the Tech Serve Solutions sales team via our website or by telephone.
▶ Related products

1-(2-Fluorobenzyl)piperazine
C11H15FN2
Chemical Synthesis
1-(2-Fluorophenyl)biguanide hydrochloride
Chemical Synthesis

1-(2-Fluorophenyl)cyclopropanecarboxylic acid
C10H9FO2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine
C10H13FN2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine monohydrochloride
C10H13FN2 · HCl
Chemical Synthesis
1-(2-Furoyl)-1H-benzotriazole
C11H7N3O2
Chemical Synthesis
1-(2-Furoyl)piperazine
C9H12N2O2
Chemical Synthesis
1-(2-Hydroxy-5-methylphenyl)-3-phenyl-1,3-propanedione
Chemical Synthesis



