Symadex
Symadex (CAS: 138154-39-9), with the molecular formula C20H22N4O2, is a chemical compound identified as a modulators for MRP transporters and a tyrosine kinase inhibitor. It presents as a white to beige powder and is primarily utilised in biochemical research for its role in cell signaling pathways and drug efflux pump studies. Its molecular weight is 350.41 g/mol.
- IUPAC
- 5-[[2-(Diethylamino)ethyl]amino]-8-hydroxy-6H-Imidazo[4,5,1-de]acridin-6-one,C-1311,C1311
- Synonyms
- C-1311C13115-[[2-(Diethylamino)ethyl]amino]-8-hydroxy-6H-Imidazo[4,5,1-de]acridin-6-one

Drug Efflux Pump Research
Symadex serves as a valuable tool in studying the function and inhibition of multi-drug resistance (MDR) proteins, particularly the MRP transporter family. This aids in understanding drug resistance mechanisms in various biological systems.
Kinase/Phosphatase Biology Investigations
This compound is employed in research focused on kinase and phosphatase activity, contributing to the understanding of cell signaling cascades and receptor tyrosine kinase pathways. Its inhibitory properties are key to these studies.
Cell Signaling Pathway Analysis
Researchers utilise Symadex to explore complex cell signaling networks and their regulation. Its interaction with specific cellular targets provides insights into cellular communication and response mechanisms.
| Molecular weight | 350.41 |
|---|---|
| Empirical formula | C20H22N4O2 |
| Assay | ≥98% (HPLC) |
| Form | powder |
| Colour | white to beige |
| Solubility | DMSO: soluble10 mg/mL (clear solution; warmed) |
| Storage temperature | 2-8°C |

Hazard statements
- H302Harmful if swallowed
| Water hazard class (WGK, DE) | 3 |
|---|---|
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Symadex used for?
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Symadex is used in research, particularly in the study of cell signaling, neuroscience, drug efflux pumps, and kinase/phosphatase biology. It acts as a modulator for MRP transporters and a receptor tyrosine kinase inhibitor.
What are the CAS number and formula for Symadex?
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The CAS number for Symadex is 138154-39-9, and its molecular formula is C20H22N4O2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Symadex with a purity of ≥98% as determined by HPLC. This product is intended for research and laboratory use. TSS does not represent this product as USP, BP, EP, or other pharmacopoeial grades.
How should Symadex be handled and stored?
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Symadex is classified as harmful if swallowed (H302). It is a white to beige powder that should be stored at 2-8°C. Handle with appropriate personal protective equipment in a well-ventilated area.
How is Symadex packed, shipped, and exported?
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Symadex is carefully packed to maintain its integrity during transit. Tech Serve Solutions has extensive experience in exporting chemicals globally, adhering to all relevant shipping regulations.
How can I request a sample or quote for Symadex?
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To request a sample or a quote for Symadex, please contact our sales team through the TSS website or by email, providing your specific requirements.
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