SPhos Pd G2
SPhos Pd G2 (CAS: 1375325-64-6), with the empirical formula C38H45ClNO2PPd and a molecular weight of 720.62 g/mol, is a highly active palladium precatalyst. As a second-generation Buchwald palladacycle, it is specifically designed for demanding cross-coupling reactions. Its robust structure and high reactivity make it an invaluable tool in modern organic synthesis, particularly for challenging Suzuki-Miyaura and Buchwald-Hartwig amination reactions, enabling efficient carbon-carbon and carbon-heteroatom bond formation.
- IUPAC
- 2nd Generation SPhos Precatalyst,Chloro(2-dicyclohexylphosphino-2′,6′-dimethoxy-1,1′-biphenyl)[2-(2′-amino-1,1′-biphenyl)]palladium(II),SPhos-Pd-G2
- Synonyms
- SPhos-Pd-G22nd Generation SPhos PrecatalystChloro(2-dicyclohexylphosphino-2′,6′-dimethoxy-1,1′-biphenyl)[2-(2′-amino-1,1′-biphenyl)]palladium(II)
Suzuki-Miyaura Cross-Coupling
SPhos Pd G2 is a highly effective catalyst for Suzuki-Miyaura reactions, facilitating the formation of C-C bonds between organoboron compounds and organic halides. It exhibits excellent activity even with sterically hindered substrates.
Buchwald-Hartwig Amination
This palladium precatalyst is widely employed in Buchwald-Hartwig amination for the construction of C-N bonds. It enables the efficient coupling of amines with aryl or heteroaryl halides.
Organic Synthesis
As a versatile homogeneous palladium catalyst, SPhos Pd G2 is instrumental in various complex organic syntheses, enabling the creation of intricate molecular architectures in pharmaceutical and fine chemical research.
| Molecular weight | 720.62 |
|---|---|
| Empirical formula | C38H45ClNO2PPd |
| Melting point | 218 °C (dec.) |
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is SPhos Pd G2 used for?
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SPhos Pd G2 is primarily used as a highly active palladium precatalyst in cross-coupling reactions, such as Suzuki-Miyaura coupling and Buchwald-Hartwig amination, for efficient carbon-carbon and carbon-heteroatom bond formation in organic synthesis.
What is the CAS number and formula for SPhos Pd G2?
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The CAS number for SPhos Pd G2 is 1375325-64-6, and its empirical formula is C38H45ClNO2PPd.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies SPhos Pd G2 as a research-grade chemical. The precise assay and purity are available on the product's specification sheet. We do not represent this product as USP, BP, or EP grade.
What are the safety and handling considerations for SPhos Pd G2?
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SPhos Pd G2 is classified under WGK Germany 3, indicating a high hazard level. Handle with appropriate personal protective equipment in a well-ventilated area, avoiding contact with skin, eyes, and clothing. Refer to the Safety Data Sheet (SDS) for detailed hazard information.
How is SPhos Pd G2 packed and exported by TSS?
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Tech Serve Solutions expertly packs and exports SPhos Pd G2, adhering to all relevant regulations for chemical transport and international shipping to ensure safe and compliant delivery worldwide.
How can I request a quote or sample for SPhos Pd G2?
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To request a quote or a sample of SPhos Pd G2, please contact our sales team through the website or by phone, providing the product name and CAS number (1375325-64-6).
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