(SP,S′P)-1,1′-Bis{bis[3,5-bis(trifluoromethyl)phenyl]phosphino}-2,2′-bis[(R)-α-(dimethylamino)benzyl]ferrocene
(SP,S′P)-1,1′-Bis{bis[3,5-bis(trifluoromethyl)phenyl]phosphino}-2,2′-bis[(R)-α-(dimethylamino)benzyl]ferrocene (CAS 494227-36-0) is a sophisticated chiral ferrocenyl ligand with the molecular formula C60H42F24FeN2P2 and a molecular weight of 1364.74 g/mol. This high-purity compound is instrumental in asymmetric synthesis, enabling enantioselective transformations crucial for the development of pharmaceuticals and fine chemicals. Its unique structure facilitates efficient catalysis.
- IUPAC
- (1R,1′R)-1,1′-Bis[bis[3,5-bis(trifluoromethyl)phenyl]phosphino]-2,2′-bis[(R)-(dimethylamino)phenylmethyl]ferrocene (acc to CAS),Mandyphos SL-M003-1
- Synonyms
- 494227-36-0(SP,S′P)-1,1′-Bis{bis[3,5-bis(trifluoromethyl)phenyl]phosphino}-2,2′-bis[(R)-α-(dimethylamino)benzyl]ferroceneC60H42F24FeN2P2
![(SP,S′P)-1,1′-Bis{bis[3,5-bis(trifluoromethyl)phenyl]phosphino}-2,2′-bis[(R)-α-(dimethylamino)benzyl]ferrocene (1′-Bis{bis[3) — chemical structure, CAS 494227-36-0; Chemistry, fine chemical supplied by Tech Serve Solutions](/_next/image?url=https%3A%2F%2Fpub-f4d920c906024441a773a96f7098e551.r2.dev%2Fimages%2Fproducts%2F494227-36-0.png&w=3840&q=75)
Asymmetric Catalysis
This ferrocenyl ligand is a highly effective chiral catalyst for various enantioselective reactions. It is particularly valuable in asymmetric hydrogenation and conjugate additions, facilitating the synthesis of enantiomerically pure compounds.
Pharmaceutical Intermediate Synthesis
Its ability to promote high enantioselectivity makes it indispensable in the multi-step synthesis of complex pharmaceutical intermediates. This leads to the efficient production of chirally pure active pharmaceutical ingredients (APIs).
Fine Chemical Manufacturing
The ligand's performance in chiral induction is leveraged in the manufacture of specialised fine chemicals where specific stereoisomers are required for desired properties or functions.
Ligand for Transition Metal Catalysis
As a bidentate phosphine ligand, it forms stable complexes with transition metals, creating active catalysts for a range of organic transformations. The bulky trifluoromethylphenyl groups enhance catalytic activity and selectivity.
| Molecular weight | 1364.74 |
|---|---|
| Empirical formula | C60H42F24FeN2P2 |
| Assay | ≥97% |
| Optical purity | ee: ≥99% |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (SP,S′P)-1,1′-Bis{bis[3,5-bis(trifluoromethyl)phenyl]phosphino}-2,2′-bis[(R)-α-(dimethylamino)benzyl]ferrocene used for?
+
This compound is primarily used as a chiral ligand in asymmetric synthesis, facilitating enantioselective catalytic transformations essential for producing chirally pure pharmaceuticals and fine chemicals.
What is the CAS number and molecular formula for this ferrocene derivative?
+
The CAS number is 494227-36-0, and the molecular formula is C60H42F24FeN2P2.
What grade and purity does Tech Serve Solutions supply?
+
Tech Serve Solutions supplies this chemical with an assay of ≥97% and an optical purity of ee: ≥99%. We do not represent this product as USP, BP, or EP grade.
How should this chemical be handled safely?
+
Handle with appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter is recommended. The WGK Germany is 3, indicating a high hazard.
Is this chemical a controlled substance?
+
The provided data does not indicate that this chemical is a controlled substance.
How is this product packed and shipped?
+
Tech Serve Solutions expertly packs and exports fine chemicals, pharmaceutical intermediates, and laboratory reagents globally, ensuring safe and compliant transit.
How can I request a sample or quote?
+
Please contact our sales team through our website or direct inquiry channels to request a sample or a formal quotation for this product.
▶ Related products
1-(2-Fluorobenzyl)piperazine
C11H15FN2
Chemical Synthesis
1-(2-Fluorophenyl)biguanide hydrochloride
Chemical Synthesis
1-(2-Fluorophenyl)cyclopropanecarboxylic acid
C10H9FO2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine
C10H13FN2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine monohydrochloride
C10H13FN2 · HCl
Chemical Synthesis
1-(2-Furoyl)-1H-benzotriazole
C11H7N3O2
Chemical Synthesis
1-(2-Furoyl)piperazine
C9H12N2O2
Chemical Synthesis
1-(2-Hydroxy-5-methylphenyl)-3-phenyl-1,3-propanedione
Chemical Synthesis
▶ Explore more
3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis
3-Methyl-1,5-pentanediol
Chemical Synthesis
3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis