2-Chlorobenzylzinc chloride solution
2-Chlorobenzylzinc chloride solution (CAS: 312624-11-6; Linear Formula: ClC₆H₄CH₂ZnCl; MW: 226.42) is an organozinc halide reagent supplied by Tech Serve Solutions. This solution in THF is primarily utilized in organic synthesis as a valuable intermediate. It participates in various cross-coupling reactions, enabling the formation of carbon-carbon bonds. Its reactivity makes it suitable for the introduction of the 2-chlorobenzyl group into complex molecular structures, aiding in the synthesis of pharmaceuticals and fine chemicals.
Organometallic Synthesis
2-Chlorobenzylzinc chloride solution serves as a key reagent in organometallic chemistry. It is employed in diverse cross-coupling reactions, such as Negishi couplings, facilitating the formation of new carbon-carbon bonds.
Pharmaceutical Intermediate Synthesis
This organozinc compound is instrumental in the synthesis of complex organic molecules, including potential pharmaceutical intermediates. Its controlled reactivity allows for selective functionalization in multi-step synthetic pathways.
Fine Chemical Production
The reagent is applicable in the manufacturing of fine chemicals, where the precise introduction of the 2-chlorobenzyl moiety is required. It aids in building molecular complexity for specialised chemical products.
| Molecular weight | 226.42 |
|---|---|
| Linear formula | ClC6H4CH2ZnCl |
| Density | 0.975 g/mL at 25 °C |
| Concentration | 0.5 M in THF |
| Storage temperature | 2-8°C |
Hazard statements
- H225Highly flammable liquid and vapour
- H319Causes serious eye irritation
- H335May cause respiratory irritation
- H351Suspected of causing cancer
Precautionary statements
- P210Keep away from heat, sparks and open flames. No smoking
- P261Avoid breathing dust, fume, gas or vapours
- P281Use personal protective equipment as required
- P305IF IN EYES
| Flash point | -17 °C / 1.4 °F |
|---|---|
| Transport (UN / ADR) | UN 2924 8(3) / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | F,Xn |
| Risk statements (R) | 11-14-19-36/37-40 |
| Safety statements (S) | 16-26-36/37 |
| Supplemental hazards | May form explosive peroxides. |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Chlorobenzylzinc chloride solution used for?
+
2-Chlorobenzylzinc chloride solution (CAS: 312624-11-6) is primarily used in organic synthesis, particularly in cross-coupling reactions like Negishi couplings, for the formation of carbon-carbon bonds and the introduction of the 2-chlorobenzyl group in the synthesis of pharmaceuticals and fine chemicals.
What is the CAS number and formula for 2-Chlorobenzylzinc chloride solution?
+
The CAS number is 312624-11-6, and the linear formula is ClC₆H₄CH₂ZnCl.
What grade and purity does Tech Serve Solutions supply for 2-Chlorobenzylzinc chloride solution?
+
Tech Serve Solutions supplies 2-Chlorobenzylzinc chloride solution at a concentration of 0.5 M in THF. This is a technical/research grade material, and TSS does not represent it as USP, BP, or EP grade.
What are the primary safety concerns when handling 2-Chlorobenzylzinc chloride solution?
+
This product is highly flammable (H225) and can cause serious eye irritation (H319) and respiratory irritation (H335). It is also suspected of causing cancer (H351). It may form explosive peroxides. Handling requires strict adherence to safety protocols, including working in a well-ventilated area, avoiding ignition sources, and using appropriate personal protective equipment.
How is 2-Chlorobenzylzinc chloride solution packed and shipped?
+
2-Chlorobenzylzinc chloride solution is packed and shipped according to international regulations for hazardous materials. It is classified under UN 2924, Hazard Class 8(3), Packing Group II, indicating it is a corrosive liquid, flammable, and toxic.
How can I request a sample or quote for 2-Chlorobenzylzinc chloride solution?
+
To request a sample or quote for 2-Chlorobenzylzinc chloride solution, please contact the Tech Serve Solutions sales team through our website or by phone, providing the product name and CAS number.
▶ Related products
1-(2-Fluorobenzyl)piperazine
C11H15FN2
Chemical Synthesis
1-(2-Fluorophenyl)biguanide hydrochloride
Chemical Synthesis
1-(2-Fluorophenyl)cyclopropanecarboxylic acid
C10H9FO2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine
C10H13FN2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine monohydrochloride
C10H13FN2 · HCl
Chemical Synthesis
1-(2-Furoyl)-1H-benzotriazole
C11H7N3O2
Chemical Synthesis
1-(2-Furoyl)piperazine
C9H12N2O2
Chemical Synthesis
1-(2-Hydroxy-5-methylphenyl)-3-phenyl-1,3-propanedione
Chemical Synthesis
▶ Explore more
3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis
3-Methyl-1,5-pentanediol
Chemical Synthesis
3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis