2-Chlorochalcone, predominantly trans
2-Chlorochalcone (CAS: 22966-11-6) is a chemical compound with the linear formula ClC6H4CH=CHCOC6H5 and a molecular weight of 242.70 g/mol. This predominantly trans isomer is a valuable building block and ketone, widely utilised in organic synthesis. Its applications span various chemical research and development processes, contributing to the creation of more complex molecular structures.
- IUPAC
- 3-(2-Chlorophenyl)-1-phenyl-2-propen-1-one
- Synonyms
- 3-(2-Chlorophenyl)-1-phenyl-2-propen-1-one

Organic Synthesis Intermediate
2-Chlorochalcone serves as a key intermediate in the synthesis of diverse organic compounds. Its reactive nature allows for further functionalisation, enabling the construction of complex molecular frameworks for research purposes.
Research and Development
Utilised in laboratory settings, this compound is essential for R&D activities, particularly in areas exploring novel chemical pathways and material science.
Carbonyl Chemistry
As a ketone, 2-Chlorochalcone participates in various reactions characteristic of carbonyl compounds, facilitating studies in reaction mechanisms and synthetic methodologies.
| Molecular weight | 242.70 |
|---|---|
| Linear formula | ClC6H4CH=CHCOC6H5 |
| Assay | 98% |
| Melting point | 49-52 °C(lit.) |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Flash point | 113 °C / 235.4 °F |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Chlorochalcone predominantly used for?
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2-Chlorochalcone is primarily used as an intermediate in organic synthesis and for general chemical research and development activities.
What are the CAS number and chemical formula for 2-Chlorochalcone?
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The CAS number for 2-Chlorochalcone is 22966-11-6, and its linear chemical formula is ClC6H4CH=CHCOC6H5.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2-Chlorochalcone with an assay of 98%. We do not represent this product as USP, BP, or EP grade.
How should 2-Chlorochalcone be handled?
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Handle 2-Chlorochalcone with appropriate personal protective equipment, including a dust mask (type N95 US), eyeshields, and gloves. Avoid breathing dust. Ensure adequate ventilation. Refer to the safety data sheet for comprehensive handling guidelines.
Does TSS export 2-Chlorochalcone?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including 2-Chlorochalcone.
How can I request a quote or sample for 2-Chlorochalcone?
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Please contact our sales team via the website or phone to request a quote or sample for 2-Chlorochalcone.
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