2-Chlorobenzylsulfonyl chloride
2-Chlorobenzylsulfonyl chloride (CAS: 77421-13-7, C7H6Cl2O2S) is a reactive organic compound with a molecular weight of 225.09 g/mol. As a sulfonyl halide, it serves as a valuable building block in organic synthesis. Its primary application lies in the preparation of diverse organic molecules, particularly those involving the introduction of the 2-chlorobenzylsulfonyl moiety. This compound is supplied by Tech Serve Solutions for research and development purposes.
- IUPAC
- (2-Chlorophenyl)methanesulfonyl chloride,2-Chlorobenzenemethanesulfonyl chloride,2-Chloro-α-toluenesulfonyl chloride
- Synonyms
- (2-Chlorophenyl)methanesulfonyl chloride2-Chlorobenzenemethanesulfonyl chloride2-Chloro-α-toluenesulfonyl chloride

Organic Synthesis Intermediate
2-Chlorobenzylsulfonyl chloride is employed as an intermediate in the synthesis of complex organic molecules. Its sulfonyl chloride group readily reacts with nucleophiles, enabling the formation of new carbon-sulfur bonds.
Building Block for Specialty Chemicals
This compound acts as a fundamental building block in the creation of specialty chemicals. Its unique structure allows for its incorporation into various molecular architectures for targeted applications.
Reagent in Pharmaceutical Research
Researchers utilise 2-Chlorobenzylsulfonyl chloride in the exploratory phases of pharmaceutical development. It can be used to construct novel molecular scaffolds or introduce specific functional groups relevant to drug discovery.
| Molecular weight | 225.09 |
|---|---|
| Empirical formula | C7H6Cl2O2S |
| Assay | 97% |
| Melting point | 59-63 °C |


Hazard statements
- H302Harmful if swallowed
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Transport (UN / ADR) | UN 3261 8 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22-34 |
| Safety statements (S) | 26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Chlorobenzylsulfonyl chloride used for?
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2-Chlorobenzylsulfonyl chloride is primarily used as a building block and intermediate in organic synthesis, particularly for the preparation of specialty chemicals and in pharmaceutical research.
What are the CAS number and formula for 2-Chlorobenzylsulfonyl chloride?
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The CAS number for 2-Chlorobenzylsulfonyl chloride is 77421-13-7, and its empirical formula is C7H6Cl2O2S.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2-Chlorobenzylsulfonyl chloride with an assay of 97%. This product is not represented as USP, BP, EP, or any other pharmacopoeia grade.
What are the safety and handling precautions for 2-Chlorobenzylsulfonyl chloride?
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2-Chlorobenzylsulfonyl chloride is a Danger hazard (GHS05, GHS07) that can cause severe skin burns and eye damage (H314) and is harmful if swallowed (H302). Recommended personal protective equipment includes a dust mask type N95 (US), eyeshields, and gloves. Handle in a well-ventilated area and seek immediate medical attention if exposed.
How is 2-Chlorobenzylsulfonyl chloride packed and shipped?
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2-Chlorobenzylsulfonyl chloride is shipped as UN 3261, Class 8, Packing Group II. Please contact TSS for detailed shipping and export information.
How can I request a quote or sample for 2-Chlorobenzylsulfonyl chloride?
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To request a quote or sample for 2-Chlorobenzylsulfonyl chloride, please contact our sales team through the website or by phone.
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