Sodium trimethylsilanolate

CAS 18027-10-6(CH3)3SiONaAcids & Bases

Sodium trimethylsilanolate (CAS 18027-10-6), with the linear formula (CH3)3SiONa and a molecular weight of 112.18, is a strong organic base. It finds application as a reagent in chemical synthesis and as a versatile building block in organic chemistry. Its properties make it valuable for specific chemical transformations where a potent, non-nucleophilic base is required. It is supplied by TSS at an assay of 95%.

IUPAC: Trimethylsilanol sodium salt

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Sodium trimethylsilanolate ((CH3)3SiONa) — chemical structure, CAS 18027-10-6; Chemistry, fine chemical supplied by Tech Serve Solutions

Acids & BasesBasesChemical SynthesisOrganic BasesSynthetic Reagents

01 /Applications

Organic Synthesis Reagent

Sodium trimethylsilanolate serves as a strong base in various organic reactions. Its sterically hindered nature can be advantageous in promoting specific transformations while minimising side reactions.

Silane Chemistry

As a salt of a silanol, it can participate in reactions involving silicon-centred species, acting as a source of the trimethylsilanolate anion for further derivatisation or functionalisation.

Deprotonation Agent

Its strong basicity allows for the deprotonation of relatively acidic protons, facilitating reactions such as alkylations, acylations, and condensations in organic synthesis.

02 /Properties

Molecular weight	112.18
Linear formula	(CH3)3SiONa
Assay	95%
Melting point	230 °C (dec.)(lit.)

03 /Safety & handling

GHS hazard pictogram: Corrosive (GHS05) — Corrosive

Danger

Hazard statements

H314Causes severe skin burns and eye damage

Precautionary statements

P280Wear protective gloves, clothing and eye/face protection
P305IF IN EYES
P310Immediately call a POISON CENTER or doctor

Protective equipment	Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges
Flash point	110 °C / 230 °F
Transport (UN / ADR)	UN 3263 8 / PGII
Water hazard class (WGK, DE)	3
Hazard codes (EU)	C
Risk statements (R)	34
Safety statements (S)	26-36/37/39-45

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

18027-10-6

MDL number

MFCD00013926

PubChem substance

24859800

Beilstein registry

3912148

05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is Sodium trimethylsilanolate used for?

Sodium trimethylsilanolate is primarily used as a strong organic base and reagent in chemical synthesis. It is valuable for deprotonation reactions and in silane chemistry.

What is the CAS number and formula for Sodium trimethylsilanolate?

The CAS number is 18027-10-6 and the linear formula is (CH3)3SiONa.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies Sodium trimethylsilanolate at an assay of 95%. This is a technical/research grade; we do not represent it as USP, BP, EP, or pharmaceutical grade.

How should Sodium trimethylsilanolate be handled safely?

Sodium trimethylsilanolate is a corrosive substance (H314). Handle with appropriate personal protective equipment, including eyeshields, face shields, and gloves, in a well-ventilated area. Avoid contact with skin, eyes, and clothing.

Is Sodium trimethylsilanolate available for export?

Yes, Tech Serve Solutions is a global supplier and exporter of fine chemicals, including Sodium trimethylsilanolate, complying with all necessary regulations for international shipment.

How can I request a sample or quote?

To request a sample or a quote for Sodium trimethylsilanolate, please contact our sales team through the website or by direct inquiry, providing your specific requirements.