Sodium tert-butoxide
Sodium tert-butoxide (CAS: 865-48-5) is a strong, sterically hindered organic base with the linear formula NaOC(CH3)3 and a molecular weight of 96.10 g/mol. It is commonly employed as a non-nucleophilic base in organic synthesis, particularly for elimination reactions and deprotonations where steric bulk is advantageous. Available as a solution in THF, it facilitates a range of chemical transformations.
Organic Synthesis Reagent
Utilised as a potent, non-nucleophilic base in various organic reactions, including elimination (E2) reactions and deprotonations of weakly acidic compounds. Its steric hindrance minimises unwanted nucleophilic attack.
Deprotonation Reactions
Effectively deprotonates a variety of substrates, such as ketones, esters, and alkynes, facilitating subsequent reactions like alkylations and aldol condensations. Its strong basicity and bulk make it ideal for challenging deprotonations.
Catalysis
Can serve as a catalyst or co-catalyst in certain polymerisation processes and other organic transformations where a strong, hindered base is required.
| Molecular weight | 96.10 |
|---|---|
| Linear formula | NaOC(CH3)3 |
| Assay | 97% |
| Density | 0.911 g/mL at 25 °C |
| Refractive index | n20/D 1.413 |
| Concentration | 2 M in THF |
Hazard statements
- H251Self-heating; may catch fire
- H314Causes severe skin burns and eye damage
Precautionary statements
- P235Keep cool
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Flash point | 14 °C / 57.2 °F |
|---|---|
| Transport (UN / ADR) | UN 3206 4.2/PG 2 |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | F,C |
| Risk statements (R) | 11-14-34-37 |
| Safety statements (S) | 7/8-26-36/37/39-43-45 |
| Supplemental hazards | Reacts violently with water. |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Sodium tert-butoxide primarily used for?
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Sodium tert-butoxide (CAS: 865-48-5) is primarily used as a strong, sterically hindered, non-nucleophilic base in organic synthesis for elimination reactions and deprotonations.
What are the CAS number and formula for Sodium tert-butoxide?
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The CAS number for Sodium tert-butoxide is 865-48-5, and its linear formula is NaOC(CH3)3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Sodium tert-butoxide with an assay of 97%. We do not represent this product as meeting pharmacopoeia standards (USP, BP, EP); it is supplied for laboratory and industrial use.
How should Sodium tert-butoxide be handled safely?
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Sodium tert-butoxide is a flammable solid that reacts violently with water and is corrosive. Handle in a well-ventilated area, away from ignition sources, and wear appropriate personal protective equipment, including gloves, eye protection, and protective clothing. Avoid contact with water and incompatible materials. Refer to the Safety Data Sheet for detailed handling procedures.
How is Sodium tert-butoxide packed and shipped?
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Sodium tert-butoxide is shipped as UN 3206, Hazard Class 4.2 (substances liable to spontaneous combustion), Packing Group II, and is often supplied as a solution in THF for ease of handling. TSS ensures compliance with all relevant shipping regulations for export.
How can I request a quote or sample for Sodium tert-butoxide?
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To request a quote or sample for Sodium tert-butoxide, please contact our sales team via the website or by phone. Please specify the quantity and your location for accurate pricing and shipping information.
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