Sodium ethoxide
Sodium ethoxide (CAS 141-52-6, CH3CH2ONa, MW 68.05) is a potent organic base and a crucial reagent in organic synthesis. It is a strong alkoxide typically supplied as a technical grade powder. Its primary utility lies in its ability to deprotonate weakly acidic compounds, making it indispensable for reactions such as condensation, alkylation, and isomerisation. This chemical is widely employed in the pharmaceutical and fine chemical industries for the synthesis of complex organic molecules.
- IUPAC
- Sodium ethylate
- Synonyms
- Sodium ethylate
Organic Synthesis
Sodium ethoxide serves as a strong base catalyst and nucleophile in numerous organic transformations. It is frequently used in Claisen condensations, Williamson ether synthesis, and as a deprotonating agent for activated methylene compounds.
Pharmaceutical Intermediates
It is instrumental in the multi-step synthesis of various pharmaceutical active ingredients. Its ability to facilitate key bond-forming reactions is vital for creating complex molecular architectures required for drug development.
Dye Manufacturing
Sodium ethoxide is employed in the production of certain dyes and pigments. It acts as a reagent in reactions that build the chromophore structures essential for colour.
Polymerisation
In specific polymerisation processes, sodium ethoxide can be utilised as an initiator or catalyst. Its strong basicity influences the rate and outcome of certain polymer formation reactions.
| Molecular weight | 68.05 |
|---|---|
| Linear formula | CH3CH2ONa |
| Assay | 95% |
| Grade | technical |
| Vapour pressure | <0.1 mmHg (20 °C) |
| Vapour density | 1.6 (vs air) |
| Impurities tested | ~2% Na2CO3 and NaOH |
Hazard statements
- H251Self-heating; may catch fire
- H314Causes severe skin burns and eye damage
Precautionary statements
- P235Keep cool
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Flash point | 30 °C / 86 °F |
|---|---|
| Transport (UN / ADR) | UN 3206 4.2/PG 2 |
| Water hazard class (WGK, DE) | 1 |
| Hazard codes (EU) | F,C |
| Risk statements (R) | 11-14-34 |
| Safety statements (S) | 8-16-26-43-45 |
| Supplemental hazards | Reacts violently with water. |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Sodium Ethoxide used for?
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Sodium ethoxide is primarily used as a strong base and nucleophile in organic synthesis, particularly for reactions like condensation, alkylation, and isomerisation. It is also important in the manufacturing of pharmaceuticals, dyes, and certain polymers.
What is the CAS number and formula for Sodium Ethoxide?
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The CAS number for Sodium Ethoxide is 141-52-6, and its chemical formula is CH3CH2ONa.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Sodium Ethoxide in a technical grade with an assay of 95%. We do not represent this product as USP, BP, or EP grade.
How should Sodium Ethoxide be handled safely?
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Sodium ethoxide is highly reactive and corrosive. It reacts violently with water, releases flammable ethanol upon contact with moisture, and can cause severe skin burns and eye damage. Always handle in a well-ventilated area, away from water and ignition sources, wearing appropriate personal protective equipment (gloves, eye protection, protective clothing).
Is Sodium Ethoxide a controlled substance?
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Based on the provided data, Sodium Ethoxide (CAS 141-52-6) is not listed as a controlled or scheduled substance.
How is Sodium Ethoxide packed and exported?
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Sodium ethoxide is classified under UN 3206, hazard class 4.2, packing group II. It is shipped and exported according to stringent international regulations for hazardous materials.
How can I request a quote or sample of Sodium Ethoxide?
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To request a quote or a sample of Sodium Ethoxide, please contact our sales team through the TSS website or via direct inquiry, specifying the required quantity and delivery details.
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