4′-(Trifluoromethyl)acetophenone
4′-(Trifluoromethyl)acetophenone (CAS 709-63-7) is an organic compound with the linear formula CF₃C₆H₄COCH₃ and a molecular weight of 188.15 g/mol. This fluorinated ketone serves as a valuable building block in organic synthesis. It is commonly employed in the preparation of more complex molecules, particularly in the fields of pharmaceuticals and materials science due to the electron-withdrawing nature of the trifluoromethyl group. It is a key intermediate in chemical synthesis.
- IUPAC
- 4-Acetylbenzotrifluoride
- Synonyms
- 4-Acetylbenzotrifluoride
Organic Synthesis Intermediate
4′-(Trifluoromethyl)acetophenone is frequently utilised as a starting material or intermediate in the synthesis of diverse organic compounds. Its reactive carbonyl group and the presence of a trifluoromethyl moiety make it ideal for constructing molecules with specific electronic and structural properties.
Pharmaceutical Research
This compound finds application in medicinal chemistry research for the development of novel pharmaceutical agents. The trifluoromethyl group can enhance lipophilicity and metabolic stability, properties desirable in drug candidates.
Materials Science
It can be used in the synthesis of advanced materials, potentially contributing to the development of functional polymers or specialised organic electronics where fluorinated components are beneficial.
| Molecular weight | 188.15 |
|---|---|
| Linear formula | CF3C6H4COCH3 |
| Assay | 98% |
| Boiling point | 79-80 °C/8 mmHg(lit.) |
| Melting point | 30-33 °C(lit.) |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Flash point | 84 °C / 183.2 °F |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4′-(Trifluoromethyl)acetophenone used for?
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4′-(Trifluoromethyl)acetophenone is primarily used as a versatile building block and intermediate in organic synthesis, particularly in the development of pharmaceuticals and materials.
What is the CAS number and chemical formula for 4′-(Trifluoromethyl)acetophenone?
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The CAS number is 709-63-7 and the linear chemical formula is CF₃C₆H₄COCH₃.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 4′-(Trifluoromethyl)acetophenone with a minimum assay of 98%. This product is supplied for laboratory and research purposes and is not represented as USP, BP, EP, or pharmaceutical grade.
How should 4′-(Trifluoromethyl)acetophenone be handled safely?
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Based on the provided safety data, 4′-(Trifluoromethyl)acetophenone is classified as a Warning. It can cause skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335). Appropriate personal protective equipment, including a dust mask type N95, eyeshields, and gloves, should be used. Handle in a well-ventilated area.
How is 4′-(Trifluoromethyl)acetophenone packed and exported by TSS?
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Tech Serve Solutions exports fine chemicals globally. Products are carefully packed according to international shipping regulations to ensure safe transit. Specific packaging details can be provided upon request.
How can I request a quote or sample for 4′-(Trifluoromethyl)acetophenone?
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To request a quote or a sample of 4′-(Trifluoromethyl)acetophenone, please use the contact form on our website or contact our sales team directly. Please specify the quantity required.
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