Sodium chenodeoxycholate
Sodium chenodeoxycholate (CAS: 2646-38-0), with the molecular formula C24H39NaO4 and a molecular weight of 414.55 g/mol, is an anionic detergent and a bile salt. It is utilised in various biochemical research applications, including studies on DNA repair mechanisms in bacteria and investigations into spore germination. Its properties as a detergent also lend themselves to applications in membrane protein solubilisation and drug delivery systems.
- IUPAC
- 3α,7α-Dihydroxy-5β-cholanic acid,5β-Cholanic acid-3α,7α-diol,Chenodeoxycholic acid sodium salt,Chenodesoxycholic acid,Chenodiol
- Synonyms
- Chenodeoxycholic acid sodium salt5β-Cholanic acid-3α,7α-diol, sodium saltChenodiol sodium salt
Biochemical Research
Sodium chenodeoxycholate is employed in laboratory studies to investigate biological processes, such as DNA repair mechanisms in microorganisms like Escherichia coli.
Spore Germination Studies
This bile salt has been used to explore the factors influencing the germination of bacterial spores, for example, those of Clostridium difficile.
Membrane Protein Solubilisation
As an anionic detergent, Sodium chenodeoxycholate is valuable for the solubilisation and study of membrane proteins in biological research.
Drug Delivery Systems
Its properties make it a component considered in the development of drug delivery vehicles, potentially including liposome-based systems.
| Molecular weight | 414.55 |
|---|---|
| Empirical formula | C24H39NaO4 |
| Assay | ≥97% |
| Application | Sodium chenodeoxycholate has been used in a study to assess DNA repair response in the bacterium Escherichia coli. 1 It has also been used in a study to investigate the physical and chemical factors influencing germination of Clostridium difficile spores. 2 |
Hazard statements
- H302Harmful if swallowed
- H312Harmful in contact with skin
- H332Harmful if inhaled
- H351Suspected of causing cancer
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P281Use personal protective equipment as required
| Water hazard class (WGK, DE) | 3 |
|---|---|
| Hazard codes (EU) | Xn |
| Risk statements (R) | 20/21/22-40 |
| Safety statements (S) | 22-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Description | anionic |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Sodium chenodeoxycholate used for?
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Sodium chenodeoxycholate is used in biochemical research, including studies on DNA repair, bacterial spore germination, membrane protein solubilisation, and drug delivery systems.
What are the CAS number and chemical formula for Sodium chenodeoxycholate?
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The CAS number for Sodium chenodeoxycholate is 2646-38-0, and its chemical formula is C24H39NaO4.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Sodium chenodeoxycholate with an assay of ≥97%. This product is intended for research and laboratory use and is not represented as USP, BP, EP, or pharmaceutical grade.
What are the safety considerations when handling Sodium chenodeoxycholate?
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Sodium chenodeoxycholate is classified with a Warning signal word and carries hazard statements H302, H312, H332, and H351, indicating it is harmful if swallowed, in contact with skin, or if inhaled, and is suspected of causing cancer. Appropriate personal protective equipment, including gloves, eye protection, and respiratory protection, should be used. Handle in a well-ventilated area.
How is Sodium chenodeoxycholate packed and shipped?
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Tech Serve Solutions carefully packs and exports fine chemicals globally, adhering to international shipping regulations for chemical products.
How can I request a quote or sample for Sodium chenodeoxycholate?
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To request a quote or a sample of Sodium chenodeoxycholate, please contact our sales team through the website or by phone.
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