Sodium cholate hydrate
Sodium cholate hydrate (CAS: 206986-87-0, Formula: C24H39NaO5 · xH2O) is an anionic, non-denaturing detergent derived from bile acids. With a molecular weight of 430.55 on an anhydrous basis, it is recognised for its utility in biochemical applications. It serves as an effective agent for the extraction of membrane proteins and is suitable for cell culture, making it a valuable reagent in research and diagnostic settings.
- IUPAC
- 3α,7α,12α-Trihydroxy-5β-cholan-24-oic acid sodium salt,Cholalic acid sodium salt
- Synonyms
- 3α,7α,12α-Trihydroxy-5β-cholan-24-oic acid sodium salt, Cholalic acid sodium salt

Membrane Protein Extraction
Sodium cholate hydrate is employed as a non-denaturing detergent for the solubilisation and extraction of membrane proteins. Its properties help to maintain protein structure and function during isolation procedures.
Cell Culture Applications
This compound is deemed suitable for use in cell culture applications. Its non-denaturing nature is advantageous when introducing it into biological systems for various research purposes.
Biochemical Reagent
As a bile salt derivative, sodium cholate hydrate functions as a versatile biochemical reagent. It is used in analytical chemistry and for applications requiring mild detergents.
Diagnostic Development
Its properties make it a useful component in the development of diagnostic assays and reagents, particularly where membrane interactions or mild solubilisation is required.
| Molecular weight | 430.55 (anhydrous basis) |
|---|---|
| Empirical formula | C24H39NaO5 · xH2O |
| Assay | ≥99% |
| Application | Non-denaturing detergent used for extraction of membrane proteins. |
| Suitability | suitable for cell culture |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Description | anionic |
|---|---|
| Mol Wt | micellar avg mol wt 900-1300 |
| Aggregation Number | 2-32-3 |
| Cmc | 9-15 mM(20-25°C) |
| Hlb | 1818 |
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Sodium cholate hydrate primarily used for?
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Sodium cholate hydrate is primarily used as a non-denaturing detergent for the extraction of membrane proteins and is suitable for cell culture applications.
What is the CAS number and formula for Sodium cholate hydrate?
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The CAS number for Sodium cholate hydrate is 206986-87-0, and its formula is C24H39NaO5 · xH2O.
What grade and purity does Tech Serve Solutions supply for Sodium cholate hydrate?
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Tech Serve Solutions supplies Sodium cholate hydrate with an assay of ≥99%. This product is generally supplied as a technical or research grade. Tech Serve Solutions does not represent this product as USP, BP, or EP grade unless explicitly stated in the product documentation.
What are the safety and handling considerations for Sodium cholate hydrate?
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Sodium cholate hydrate is classified with WGK Germany 3. Appropriate personal protective equipment, including eyeshields, gloves, and a type N95 (US) or type P1 (EN143) respirator filter, should be used when handling this chemical.
How is Sodium cholate hydrate packed and shipped?
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Sodium cholate hydrate is carefully packed and exported by Tech Serve Solutions in compliance with international shipping regulations for chemicals. Specific packaging details are available upon request.
How can I request a sample or a quote for Sodium cholate hydrate?
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To request a sample or a quote for Sodium cholate hydrate, please contact our sales team through the website or by calling us directly. Please reference the product name and CAS number.
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