Sodium bis(trimethylsilyl)amide
Sodium bis(trimethylsilyl)amide (CAS: 1070-89-9), with the formula [(CH3)3Si]2NNa and a molecular weight of 183.37 g/mol, is a powerful organic base and a versatile synthetic reagent. Supplied by Tech Serve Solutions as a 40% solution in THF, it is primarily utilised in organic synthesis for the generation of carbenes, amination of sulfenamides, and the preparation of lanthanide complexes.
- IUPAC
- Hexamethyldisilazane sodium salt
- Synonyms
- Hexamethyldisilazane sodium salt
![Sodium bis(trimethylsilyl)amide ([(CH3)3Si]2NNa) — chemical structure, CAS 1070-89-9; Chemistry, fine chemical supplied by Tech Serve Solutions](/_next/image?url=https%3A%2F%2Fpub-f4d920c906024441a773a96f7098e551.r2.dev%2Fimages%2Fproducts%2F1070-89-9.png&w=3840&q=75)
Carbene Generation
Sodium bis(trimethylsilyl)amide serves as a crucial reagent for the efficient generation of carbenes, which are highly reactive intermediates employed in various organic transformations.
Sulfenamide Amination
This compound is instrumental in the amination of sulfenamides, facilitating the introduction of nitrogen-containing functional groups into organic molecules.
Lanthanide Complex Preparation
It is employed in the synthesis of lanthanide complexes, contributing to the development of novel materials and catalysts with unique properties.
| Molecular weight | 183.37 |
|---|---|
| Linear formula | [(CH3)3Si]2NNa |
| Assay | 95% |
| Density | 0.761 g/mL at 25 °C |
| Concentration | 40% in THF |
| Storage temperature | 2-8°C |
| Application | Useful for the generation of carbenes,1 the amination of sulfenamides,2 and the preparation of lanthanide complexes.3 |
| Melting point | 171-175 °C(lit.) |
Hazard statements
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges |
|---|---|
| Transport (UN / ADR) | UN 3263 8 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 14-34 |
| Safety statements (S) | 26-36/37/39-45 |
| Supplemental hazards | Reacts violently with water. |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Sodium bis(trimethylsilyl)amide used for?
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Sodium bis(trimethylsilyl)amide is used for the generation of carbenes, the amination of sulfenamides, and the preparation of lanthanide complexes.
What are the CAS number and chemical formula for Sodium bis(trimethylsilyl)amide?
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The CAS number is 1070-89-9 and the chemical formula is [(CH3)3Si]2NNa.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Sodium bis(trimethylsilyl)amide with an assay of 95%, as a 40% solution in THF. This is considered a technical/research grade and is not represented as USP/BP/EP.
How should Sodium bis(trimethylsilyl)amide be handled safely?
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Sodium bis(trimethylsilyl)amide is a Danger hazard (GHS05) that reacts violently with water (H314). Handling requires appropriate personal protective equipment, including eyeshields, face shields, gloves, and suitable respiratory protection. Ensure no contact with water.
Is Sodium bis(trimethylsilyl)amide regulated or a controlled substance?
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The provided data does not indicate that Sodium bis(trimethylsilyl)amide is a controlled substance. Please consult relevant local regulations for specific import/export requirements.
How is Sodium bis(trimethylsilyl)amide packed, shipped, or exported?
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Sodium bis(trimethylsilyl)amide is shipped under UN 3263, Hazard Class 8, Packing Group II. Please contact TSS for specific details on export packaging and compliance.
How can I request a sample or quote for Sodium bis(trimethylsilyl)amide?
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To request a sample or a quote for Sodium bis(trimethylsilyl)amide, please contact the Tech Serve Solutions sales team through our website or direct contact details.
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