Sodium amide
Sodium amide (CAS 7782-92-5), with the linear formula NaNH2 and a molecular weight of 39.01 g/mol, is a powerful inorganic base and a highly reactive chemical. It is a key reagent in various organic syntheses, particularly for the preparation of allylic amines and amides, antibacterials, and in heterocyclic chemistry. Sodium amide is supplied by TSS with an assay of 95%.
Synthesis of Allylic Amines and Amides
Sodium amide serves as a crucial reagent for the synthesis of complex allylic amines and amides, which are valuable intermediates in pharmaceutical and agrochemical development.
Antibacterial Synthesis
This compound is employed in the synthetic pathways leading to various antibacterial agents, contributing to the development of new antimicrobial therapies.
Heterocyclic Chemistry
Its strong basicity makes sodium amide an effective reagent for aggregative activation and in the formation of various heterocyclic compounds.
Phenylation Reactions
Sodium amide can be utilized in phenylation reactions, such as those involving diphenyliodonium chloride, to introduce phenyl groups into organic molecules.
| Molecular weight | 39.01 |
|---|---|
| Linear formula | NaNH2 |
| Assay | 95% |
| Boiling point | 400 °C(lit.) |
| Application | Reagent for: Synthesis of allylic amines and amides1 Synthesis of antibacterials2 Aggregative activation and heterocyclic chemistry3 Phenylation with diphenyliodonium chloride4 |
| Melting point | 210 °C(lit.) |
Hazard statements
- H225Highly flammable liquid and vapour
- H261In contact with water releases flammable gas
- H304May be fatal if swallowed and enters airways
- H314Causes severe skin burns and eye damage
- H336May cause drowsiness or dizziness
- H361D
- H373May cause damage to organs through prolonged exposure
- H400Very toxic to aquatic life
Precautionary statements
- P231Handle under inert gas
- P273Avoid release to the environment
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
- P422
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 4 °C / 39.2 °F |
| Transport (UN / ADR) | UN 3129 4.3/PG 2 |
| Water hazard class (WGK, DE) | 2 |
| Hazard codes (EU) | F,C,N |
| Risk statements (R) | 63-11-14/15-19-29-34-48/20-50-65-67 |
| Safety statements (S) | 26-36/37/39-43-45-61-62 |
| Supplemental hazards | Contact with water liberates toxic gas., May form explosive peroxides. |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Sodium amide used for?
+
Sodium amide (CAS 7782-92-5) is used as a reagent in organic synthesis, notably for preparing allylic amines and amides, antibacterials, in heterocyclic chemistry, and in phenylation reactions.
What are the CAS number and formula for Sodium amide?
+
The CAS number for Sodium amide is 7782-92-5, and its linear formula is NaNH2.
What grade and purity does Tech Serve Solutions supply?
+
Tech Serve Solutions supplies Sodium amide with an assay of 95%. We do not represent this product as USP, BP, or EP grade.
How should Sodium amide be handled safely?
+
Sodium amide is a highly reactive and dangerous substance. It is flammable (flash point 4 °C), reacts violently with water releasing toxic gas, and is corrosive. It may form explosive peroxides. Strict adherence to safety protocols, including the use of appropriate personal protective equipment such as gloves, goggles, face shields, and respirators, is mandatory. Handle under an inert atmosphere.
How is Sodium amide packed, shipped, and exported?
+
Sodium amide is shipped as UN 3129, Hazard Class 4.3 (Dangerous when wet). TSS adheres to all international regulations for the safe packing, shipping, and export of hazardous chemicals.
How can I request a sample or quote for Sodium amide?
+
To request a sample or a quote for Sodium amide, please use the contact form on our website or call our sales team directly, referencing product code 7782-92-5.
▶ Related products
5-Sulfosalicylic acid dihydrate
HO3SC6H3-2-(OH)CO2H 2H2O
Acids & Bases
Calcium hydroxide
Ca(OH)2
Acids & Bases
Acetic acid-12C2
12CH312CO2H
Acids & Bases
Acetic acid-13C2
13CH313CO2H
Acids & Bases
Acetic acid-13C2,d4
Acids & Bases
Acetic acid-17O2
CH3C17O2H
Acids & Bases
Acetic acid-18O2
CH3C18O2H
Acids & Bases
Acetic acid-2,2,2-d3
2-d3
Acids & Bases▶ Explore more
3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis
3-Methyl-1,5-pentanediol
Chemical Synthesis
3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis