Serotonin hydrochloride
Serotonin hydrochloride (CAS: 153-98-0), with the molecular formula C10H12N2O · HCl and a molecular weight of 212.68 g/mol, is a significant biochemical compound. It serves as a crucial building block in chemical synthesis and plays a vital role in cell biology research. Its applications extend to various areas of scientific investigation where its biological activity is of interest.
- IUPAC
- 3-(2-Aminoethyl)-5-hydroxyindole hydrochloride,5-HT,5-Hydroxytryptamine hydrochloride
- Synonyms
- 5-Hydroxytryptamine hydrochloride5-HT hydrochloride3-(2-Aminoethyl)-5-hydroxyindole hydrochloride

Chemical Synthesis
Serotonin hydrochloride is utilised as a versatile building block in the synthesis of more complex organic molecules. Its indole structure and amine group offer reactive sites for various chemical transformations.
Cell Biology Research
This compound is frequently employed in cell biology studies to investigate neurotransmission pathways and cellular signalling. It is valuable for understanding the physiological roles of serotonin in biological systems.
Biochemical Research
As a bioactive small molecule, serotonin hydrochloride is instrumental in biochemical research. It aids in the study of receptor interactions and enzyme activities related to monoamine metabolism.
| Molecular weight | 212.68 |
|---|---|
| Empirical formula | C10H12N2O · HCl |
| Assay | ≥98.0% (HPLC) |
| Solubility | H2O: soluble17 mg/mL0.1 M HCl: soluble22 mg/mLethanol: soluble5.3 mg/mL |
| Storage temperature | 2-8°C |
| Impurities tested | <5% water |
| Melting point | 149-154 °C(lit.) |

Hazard statements
- H302Harmful if swallowed
- H312Harmful in contact with skin
- H315Causes skin irritation
- H319Causes serious eye irritation
- H332Harmful if inhaled
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 20/21/22-36/37/38 |
| Safety statements (S) | 22-26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Serotonin hydrochloride used for?
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Serotonin hydrochloride is used in chemical synthesis as a building block and in cell biology and biochemical research to study neurotransmission, cellular signalling, and receptor interactions.
What is the CAS number and formula for Serotonin hydrochloride?
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The CAS number for Serotonin hydrochloride is 153-98-0, and its formula is C10H12N2O · HCl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Serotonin hydrochloride with an assay of ≥98.0% (HPLC). We do not represent this product as USP, BP, EP, or any other pharmacopoeia grade.
How should Serotonin hydrochloride be handled?
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Serotonin hydrochloride is classified as harmful if swallowed, in contact with skin, or if inhaled, and causes skin and eye irritation, and respiratory irritation. Handle with appropriate personal protective equipment, including a dust mask (N95), eyeshields, and gloves, in a well-ventilated area.
Is Serotonin hydrochloride a controlled substance?
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The provided data does not indicate that Serotonin hydrochloride is a controlled substance.
How is Serotonin hydrochloride shipped?
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Serotonin hydrochloride is typically stored at 2-8°C. TSS exports globally, ensuring appropriate packaging and documentation for international chemical shipments.
How can I request a quote or sample?
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To request a quote or sample of Serotonin hydrochloride, please contact the TSS sales team through our website or by phone.
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