(−)-Scopolamine hydrobromide trihydrate
(−)-Scopolamine hydrobromide trihydrate (CAS 6533-68-2, C17H21NO4 · HBr · 3H2O, MW 438.31) is a white to off-white powder. This alkaloid, also known as hyoscine hydrobromide, is soluble in water and exhibits specific optical activity. Its applications span diverse research areas, including cell biology, neuroscience, and cancer research, where it acts as a cholinergic antagonist and is investigated for potential antitumor properties.
- IUPAC
- Hyoscine hydrobromide,Scopine tropate
- Synonyms
- Hyoscine hydrobromideScopine tropate hydrobromide
Neuroscience Research
Utilised as a cholinergic antagonist in studies of neurotransmission and neuronal signalling. It serves as a valuable tool for investigating muscarinic acetylcholine receptors and their role in various neurological processes.
Cancer Research
Investigated for its potential antitumor activity. Its biological activity makes it a subject of interest in exploring novel therapeutic adjuncts within cancer research programs.
Cell Biology Studies
Employed in research settings to probe cellular mechanisms and signaling pathways. Its well-defined biochemical properties facilitate its use in diverse cell-based assays.
Pharmacological Investigations
Serves as a reference compound and research tool in pharmacology, particularly for studies involving cholinergic systems and antagonists.
| Molecular weight | 438.31 |
|---|---|
| Empirical formula | C17H21NO4 · HBr · 3H2O |
| Assay | ≥98% (HPLC) |
| Form | powder |
| Colour | white to off-white |
| Solubility | H2O: soluble50 mg/mL |
| Optical activity | [α]25/D −24 to −26°, c = 5 in H2O(lit.) |
| Melting point | 195-199 °C (dry matter)(lit.) |
Hazard statements
- H300Fatal if swallowed
- H310Fatal in contact with skin
- H330Fatal if inhaled
Precautionary statements
- P260Do not breathe dust, fume, gas, mist, vapours or spray
- P264Wash thoroughly after handling
- P280Wear protective gloves, clothing and eye/face protection
- P284Wear respiratory protection
- P301IF SWALLOWED
- P302IF ON SKIN
| Protective equipment | Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges |
|---|---|
| Transport (UN / ADR) | UN 1544 6.1/PG 3 |
| Water hazard class (WGK, DE) | 1 |
| Hazard codes (EU) | T+ |
| Risk statements (R) | 26/27/28 |
| Safety statements (S) | 25-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Gene Information | human ... CHRM1(1128), CHRM2(1129), CHRM3(1131), CHRM4(1132), CHRM5(1133) |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (–)-Scopolamine hydrobromide trihydrate used for?
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It is used in neuroscience research for studying neurotransmission and neuronal signalling, in cancer research for potential antitumor activity, and in cell biology for investigating cellular mechanisms. It acts as a cholinergic antagonist.
What are the CAS number and formula for (–)-Scopolamine hydrobromide trihydrate?
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The CAS number is 6533-68-2 and the formula is C17H21NO4 · HBr · 3H2O.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies (–)-Scopolamine hydrobromide trihydrate with a purity of ≥98% (HPLC). We do not represent this product as USP, BP, EP, or any other pharmacopoeia grade.
How is (–)-Scopolamine hydrobromide trihydrate handled and shipped?
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This compound is classified under UN 1544, Hazard Class 6.1, Packing Group III, indicating it is toxic. Handling requires stringent safety precautions, including appropriate personal protective equipment such as eyeshields, gloves, and respiratory protection. It is shipped in compliance with regulations for toxic substances.
What are the primary hazards associated with (–)-Scopolamine hydrobromide trihydrate?
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This substance is acutely toxic if swallowed, in contact with skin, or if inhaled, indicated by GHS06 signal word 'Danger' and hazard statements H300, H310, H330.
How can I request a sample or quote for (–)-Scopolamine hydrobromide trihydrate?
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Please contact our sales team via the website or direct email to request a sample or obtain a quotation. Provide your specific requirements, including quantity and delivery location.
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