SC 19220
SC 19220 is a chemical compound with the CAS number 19395-87-0 and molecular formula C16H14N3O3Cl. This white solid, with a molecular weight of 331.75 g/mol, is primarily utilised in research settings. It has been employed to investigate the involvement of prostaglandin E2 in neurotoxicity and neuroprotection mechanisms within neuronal cultures, contributing to a deeper understanding of cellular signaling pathways.
- IUPAC
- 2-Acetylhydrazide 10(11H)-carboxylic acid,8-Chloro-dibenz[b,f][1,4]oxazepine-10(11H)-carboxylic acid

Neuroscience Research
SC 19220 has been used to study the role of prostaglandin E2 in oxygen-glucose deprivation-induced neurotoxicity and preconditioning-induced neuroprotection in rat cortical cultures. This application aids in understanding cellular responses to ischemic conditions.
Cell Biology Studies
As a bioactive small molecule within the Arachidonic Acid Cascade, SC 19220 can be applied to studies concerning cell signaling, particularly lipids in cell signaling. Its use helps elucidate complex cellular mechanisms.
Prostaglandin Research
The compound serves as a tool in research focused on prostaglandins, specifically their influence on cellular processes. Its application is crucial for dissecting the signalling pathways mediated by these lipid compounds.
| Molecular weight | 331.75 |
|---|---|
| Empirical formula | C16H14N3O3Cl |
| Assay | ≥98% (HPLC) |
| Form | solid |
| Colour | white |
| Solubility | DMSO: soluble10 mg/mLH2O: insoluble |
| Application | SC 19220 was used to study the role of prostaglandin E2 in oxygen-glucose deprivation-induced neurotoxicity and preconditioning-induced neuroprotection in rat cortical cultures.1, |
| Melting point | 190-191 °C(lit.) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Gene Information | human ... PTGER1(5731)rat ... Ptger1(25637) |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is SC 19220 used for?
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SC 19220 is used in research, notably to study the role of prostaglandin E2 in neurotoxicity and neuroprotection in neuronal cultures. It is part of research into the Arachidonic Acid Cascade and cellular signaling.
What are the CAS number and formula for SC 19220?
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The CAS number for SC 19220 is 19395-87-0, and its molecular formula is C16H14N3O3Cl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies SC 19220 with a purity of ≥98% (HPLC). This product is intended for research purposes and is not represented as USP, BP, EP, or other pharmacopoeial grades.
What are the safety and handling requirements for SC 19220?
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Handling SC 19220 requires appropriate personal protective equipment, including eyeshields, gloves, and a type N95 (US) or type P1 (EN143) respirator filter. It has a WGK Germany rating of 3, indicating it is hazardous to water.
How is SC 19220 packed and shipped?
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SC 19220 is typically supplied as a white solid. Tech Serve Solutions, as a global supplier and exporter, ensures appropriate packaging and adherence to regulations for international shipment.
How can I request a sample or quote for SC 19220?
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To request a sample or quote for SC 19220, please contact the Tech Serve Solutions sales department through the website or designated contact channels.
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