S32826 disodium salt hydrate
S32826 disodium salt hydrate (CAS: 1096770-84-1 for free acid) is a potent inhibitor of autotaxin (ATX), an enzyme crucial for lysophosphatidic acid (LPA) formation. With the molecular formula C21H34NNa2O4P · xH2O, this white powder, assaying ≥98% (HPLC), is vital for researching ATX's role in cellular processes. It is used to investigate tumorigenesis, cell invasion, metastases, and cardiovascular conditions like cardia bifida and atherosclerosis.
- IUPAC
- [4-(Tetradecanoylamino)benzyl]phosphonic acid disodium salt hydrate
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Autotaxin (ATX) Inhibition Studies
S32826 serves as a potent inhibitor of autotaxin (ATX), enabling researchers to investigate its role in the production of bioactive lysophosphatidic acid (LPA). This allows for a detailed understanding of ATX-mediated signalling pathways.
Cancer Research
This compound can be employed to study the involvement of ATX in malignant cellular behaviours, including tumorigenesis, cellular invasion, and the formation of metastases. Understanding ATX's contribution is key to developing novel therapeutic strategies.
Cardiovascular Disease Research
S32826 may be utilised to explore the function of ATX in conditions such as cardia bifida and atherosclerosis. Its application aids in elucidating the molecular mechanisms underlying these cardiovascular pathologies.
Cellular Signaling and Neuroscience Research
As a modulator of lipid signaling, S32826 is valuable for investigating complex cellular processes within the realms of cell biology and neuroscience. Its specific inhibitory action provides a tool for dissecting signaling cascades.
| Molecular weight | 441.45 (anhydrous basis) |
|---|---|
| Empirical formula | C21H34NNa2O4P · xH2O |
| Assay | ≥98% (HPLC) |
| Form | powder |
| Colour | white |
| Solubility | H2O: ≥10 mg/mL |
| Storage temperature | −20°C |
| Application | S32826, a potent inhibitor of autotaxin (ATX), may be used to identify and characterize the lyso-phospholipase D (lysoPLD, ATX) involved in bioactive lyso-phosphatidic acid (LPA) formation. 1 S32826 may be used to help determine the role of ATX in malignant cell processes such as tumorigenesis, invasion, and metastases; cardia bifida and atherosclerosis.2 |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Storage Condition | desiccated |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is S32826 disodium salt hydrate used for?
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S32826 disodium salt hydrate is used as a potent inhibitor of autotaxin (ATX) to study its role in bioactive lysophosphatidic acid (LPA) formation. It aids in researching malignant cell processes like tumorigenesis, invasion, and metastases, as well as cardiovascular conditions such as cardia bifida and atherosclerosis.
What is the CAS number and formula for S32826 disodium salt hydrate?
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The CAS number for the free acid form is 1096770-84-1. The empirical formula is C21H34NNa2O4P · xH2O.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies S32826 disodium salt hydrate with an assay of ≥98% (HPLC). We do not represent this product as USP, BP, EP, or any other pharmacopoeia grade.
How should S32826 disodium salt hydrate be handled?
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When handling S32826 disodium salt hydrate, it is essential to wear appropriate personal protective equipment, including eyeshields, gloves, and a type N95 (US) or type P1 (EN143) respirator filter. Store the material desiccated at -20°C.
Is S32826 disodium salt hydrate a hazardous substance?
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S32826 disodium salt hydrate has a WGK Germany rating of 3, indicating it is hazardous to water. Appropriate safety precautions must be taken during handling and disposal.
How is S32826 disodium salt hydrate shipped or exported?
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Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including S32826 disodium salt hydrate. We adhere to all international shipping and export regulations for hazardous materials.
How can I request a sample or quote for S32826 disodium salt hydrate?
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To request a sample or quote for S32826 disodium salt hydrate, please contact our sales department through the website or by calling our dedicated order line.
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