(S)-(−)-α-Methylvaline
(S)-(−)-α-Methylvaline (CAS: 53940-83-3, C6H13NO2) is a chiral, unnatural amino acid derivative with a molecular weight of 131.17 g/mol. It is primarily utilised in chemical synthesis and peptide chemistry as a building block for creating more complex molecules. Its stereochemistry makes it valuable in applications requiring specific molecular configurations, particularly within chemical biology research. Tech Serve Solutions supplies this compound with a high assay.
- IUPAC
- α-Me-Val-OH,α-Methyl-L-valine

Peptide Synthesis
Incorporation into peptide chains to create modified peptides with altered properties or biological activities. (S)-(−)-α-Methylvaline serves as a non-proteinogenic amino acid in solid-phase or solution-phase peptide synthesis.
Chemical Synthesis
Used as a chiral building block or intermediate in the synthesis of complex organic molecules. Its specific stereochemistry is essential for stereoselective reactions.
Chemical Biology Research
Employed in the development of novel bioactive compounds and probes for studying biological systems. Its unnatural structure can confer unique properties to biomolecules.
Drug Discovery
Investigated for its potential role in the synthesis of novel pharmaceutical agents. Modified amino acids like this are key in developing new drug candidates with improved pharmacokinetic profiles.
| Molecular weight | 131.17 |
|---|---|
| Empirical formula | C6H13NO2 |
| Assay | ≥98.5% (TLC)99% |
| Optical activity | [α]/D -3.5±0.5°, c = 1% in H2O |
| Impurities tested | ≤0.2% water |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (S)-(−)-α-Methylvaline used for?
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(S)-(−)-α-Methylvaline is used as a building block in chemical synthesis, particularly in peptide chemistry and chemical biology research for creating novel molecules and modified peptides.
What is the CAS number and chemical formula for (S)-(−)-α-Methylvaline?
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The CAS number is 53940-83-3, and the chemical formula is C6H13NO2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies (S)-(−)-α-Methylvaline with an assay of ≥98.5% (TLC) and 99% purity. It is supplied as a research-grade chemical and is not represented as USP, BP, or EP grade.
How should (S)-(−)-α-Methylvaline be handled safely?
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When handling (S)-(−)-α-Methylvaline, it is essential to use appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter should be used if airborne exposure is possible. Handle in a well-ventilated area.
How is (S)-(−)-α-Methylvaline packed and exported?
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(S)-(−)-α-Methylvaline is carefully packed according to international shipping regulations for chemical products and is exported globally by Tech Serve Solutions.
How can I request a sample or quote for (S)-(−)-α-Methylvaline?
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To request a sample or quote for (S)-(−)-α-Methylvaline, please contact our sales team via the website or direct email, providing your specific requirements.
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