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(S)-(−)-α-Methylbenzylamine

CAS 2627-86-3C6H5CH(CH3)NH2Chemical Synthesis

(S)-(−)-α-Methylbenzylamine (CAS: 2627-86-3; C6H5CH(CH3)NH2; MW: 121.18) is a chiral amine vital for asymmetric synthesis. As a key chiral building block and organic synthesis intermediate, it facilitates the creation of enantiomerically pure compounds. Its applications span pharmaceutical research and fine chemical manufacturing, where precise stereochemistry is paramount. Tech Serve Solutions provides this essential reagent for advanced chemical processes.

IUPAC
(S)-(−)-1-Phenylethylamine,(S)-(-)-alpha-Methylbenzylamine
Synonyms
(S)-1-Phenylethylamine(S)-(-)-1-Phenylethylamine(S)-(-)-alpha-Methylbenzylamine
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(S)-(−)-α-Methylbenzylamine (C6H5CH(CH3)NH2) — chemical structure, CAS 2627-86-3; Chemistry, fine chemical supplied by Tech Serve Solutions
AminesAsymmetric SynthesisChemical SynthesisChiral Building BlocksOrganic Building Blocks
01 /Applications

Chiral Resolving Agent

Used to separate enantiomers of racemic mixtures by forming diastereomeric salts, enabling the isolation of specific stereoisomers.

Asymmetric Synthesis

Acts as a chiral auxiliary or precursor in reactions requiring stereochemical control, leading to enantioselective product formation.

Pharmaceutical Intermediates

A fundamental building block in the synthesis pathways of various chiral active pharmaceutical ingredients (APIs).

Ligand Synthesis

Employed in the preparation of chiral ligands for asymmetric catalysis, enhancing enantioselectivity in metal-catalyzed reactions.

02 /Properties
Molecular weight121.18
Linear formulaC6H5CH(CH3)NH2
Assay98%
Boiling point187 °C(lit.)
Density0.94 g/mL at 25 °C(lit.)
Refractive indexn20/D 1.526(lit.)
Optical activity[α]20/D −39°, neat
Optical purityee: 98% (GLC)
Vapour pressure0.5 mmHg (20 °C)
Storage temperature2-8°C
03 /Safety & handling
GHS hazard pictogram: Corrosive (GHS05)
Corrosive
GHS hazard pictogram: Toxic (GHS06)
Toxic
Danger

Hazard statements

  • H302Harmful if swallowed
  • H311Toxic in contact with skin
  • H314Causes severe skin burns and eye damage

Precautionary statements

  • P280Wear protective gloves, clothing and eye/face protection
  • P305IF IN EYES
  • P310Immediately call a POISON CENTER or doctor
Flash point70 °C / 158 °F
Water hazard class (WGK, DE)1
Hazard codes (EU)C
Risk statements (R)21/22-34
Safety statements (S)26-28-36/37/39-45

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry
CAS number
2627-86-3
Beilstein registry
2204907
05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is (S)-(−)-α-Methylbenzylamine used for?

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(S)-(−)-α-Methylbenzylamine is primarily used as a chiral resolving agent, in asymmetric synthesis, for preparing pharmaceutical intermediates, and in the synthesis of chiral ligands for catalysis.

What are the CAS number and chemical formula for (S)-(−)-α-Methylbenzylamine?

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The CAS number is 2627-86-3, and its chemical formula is C6H5CH(CH3)NH2.

What grade and purity does Tech Serve Solutions supply?

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Tech Serve Solutions supplies (S)-(−)-α-Methylbenzylamine with an assay of 98%. This is a technical/research grade material and is not represented as USP, BP, or EP.

How should (S)-(−)-α-Methylbenzylamine be handled?

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(S)-(−)-α-Methylbenzylamine is classified as Dangerous. It is harmful if swallowed, toxic in contact with skin, and causes severe skin burns and eye damage (H302-H311-H314). Handle with appropriate personal protective equipment (gloves, eye protection) in a well-ventilated area and avoid contact. Seek immediate medical attention if exposed. Store at 2-8°C.

Is (S)-(−)-α-Methylbenzylamine available for export?

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Yes, Tech Serve Solutions is a global supplier and exporter of fine chemicals, including (S)-(−)-α-Methylbenzylamine, adhering to all export regulations.

How can I request a quote or sample for (S)-(−)-α-Methylbenzylamine?

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Please use the 'Request a Quote' or 'Request a Sample' button on the product page, or contact our sales team directly with your requirements.

Need (S)-(−)-α-Methylbenzylamine in a specific grade or volume?