(S)-Boc-3-(trifluoromethyl)-β-Phe-OH
(S)-Boc-3-(trifluoromethyl)-β-Phe-OH (CAS: 500770-78-5) is a trifluoromethylated unnatural beta-amino acid derivative with the formula C15H18F3NO4 and a molecular weight of 333.30 g/mol. It is characterised by its Boc-protected amine and trifluoromethyl group. This compound finds application in chemical synthesis, particularly in peptide chemistry and the development of novel chemical entities within chemical biology research.
- IUPAC
- (S)-3-(Boc-amino)-3-[3-(trifluoromethyl)phenyl]propionic acid,Boc-3-(trifluoromethyl)-D-β-phenylalanine

Peptide Chemistry
Incorporation into peptide sequences to modify structural and functional properties, enabling the study of peptidomimetics and novel bioactive peptides.
Chemical Synthesis
Serves as a versatile building block for the synthesis of complex organic molecules, including pharmaceuticals and research chemicals.
Chemical Biology
Utilised in the design and synthesis of modified biomolecules for investigating biological processes and developing new therapeutic agents.
Unnatural Amino Acid Derivatives
Key component in the synthesis of non-proteinogenic amino acids, expanding the chemical space for drug discovery and materials science.
| Molecular weight | 333.30 |
|---|---|
| Empirical formula | C15H18F3NO4 |
| Assay | ≥98.0% |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (S)-Boc-3-(trifluoromethyl)-β-Phe-OH used for?
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(S)-Boc-3-(trifluoromethyl)-β-Phe-OH is primarily used as a building block in chemical synthesis, peptide chemistry, and chemical biology research for creating novel molecules and peptidomimetics.
What are the CAS number and formula for this compound?
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The CAS number is 500770-78-5, and the empirical formula is C15H18F3NO4.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies (S)-Boc-3-(trifluoromethyl)-β-Phe-OH with an assay of ≥98.0%. This product is typically supplied for research and development purposes and is not represented as USP, BP, EP, or pharmaceutical grade.
How should (S)-Boc-3-(trifluoromethyl)-β-Phe-OH be handled?
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Appropriate personal protective equipment, including eyeshields and gloves, should be worn. A type N95 (US) or type P1 (EN143) respirator filter is recommended. This compound is classified under WGK 2 in Germany, indicating it is hazardous to water.
Is this compound packed and shipped internationally?
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Yes, Tech Serve Solutions specialises in the global supply and export of fine chemicals like (S)-Boc-3-(trifluoromethyl)-β-Phe-OH.
How can I request a sample or a quote for (S)-Boc-3-(trifluoromethyl)-β-Phe-OH?
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Please contact our sales team or use the online enquiry form to request a sample or obtain a quotation.
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