(S)-Boc-3-(trifluoromethyl)-β-Homophe-OH
(S)-Boc-3-(trifluoromethyl)-β-Homophe-OH (CAS: 270065-77-5) is a trifluoromethyl-substituted unnatural beta-amino acid derivative. With the molecular formula C16H20F3NO4 and a molecular weight of 347.33, this compound is synthesised for research and development. It serves as a valuable building block in chemical synthesis, particularly within peptide chemistry and chemical biology, contributing to the creation of novel molecular structures.
- IUPAC
- (S)-3-(Boc-amino)-4-[3-(trifluoromethyl)phenyl]butyric acid,Boc-3-(trifluoromethyl)-L-β-homophenylalanine

Chemical Synthesis
Utilised as a chiral building block in the synthesis of complex organic molecules. Its unique structure, featuring a trifluoromethyl group and a beta-amino acid core, allows for the introduction of specific functionalities.
Peptide Chemistry
Incorporated into peptide sequences to create modified peptides with altered conformational properties or enhanced biological activity. This unnatural amino acid derivative can lead to peptidomimetics with improved stability or pharmacokinetic profiles.
Chemical Biology
Employed in the design and synthesis of probes or labelled molecules for studying biological systems. The trifluoromethyl group can serve as a reporter or influence the molecule's interaction with biological targets.
Unnatural Amino Acid Research
Serves as a key intermediate for researchers exploring the incorporation of non-proteinogenic amino acids into novel scaffolds. This aids in the development of new materials or therapeutic agents.
| Molecular weight | 347.33 |
|---|---|
| Empirical formula | C16H20F3NO4 |
| Assay | ≥98.0% (HPLC) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (S)-Boc-3-(trifluoromethyl)-β-Homophe-OH used for?
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(S)-Boc-3-(trifluoromethyl)-β-Homophe-OH is primarily used as a chiral building block in chemical synthesis, particularly within peptide chemistry and chemical biology. It is valuable for creating modified peptides and unnatural amino acid derivatives for research and development purposes.
What is the CAS number and formula for (S)-Boc-3-(trifluoromethyl)-β-Homophe-OH?
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The CAS number for (S)-Boc-3-(trifluoromethyl)-β-Homophe-OH is 270065-77-5 and its empirical formula is C16H20F3NO4.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies (S)-Boc-3-(trifluoromethyl)-β-Homophe-OH with an assay of ≥98.0% (HPLC). We do not represent this product as USP, BP, EP, or any other pharmacopoeia grade.
What are the safety and handling recommendations for this compound?
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This compound requires appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter is recommended. It has a WGK Germany rating of 3, indicating a high hazard to water.
How is (S)-Boc-3-(trifluoromethyl)-β-Homophe-OH packed, shipped, and exported?
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Tech Serve Solutions packs, ships, and exports (S)-Boc-3-(trifluoromethyl)-β-Homophe-OH with rigorous quality control measures to ensure product integrity during transit. We comply with all international shipping regulations for chemical compounds.
How can I request a sample or quote for (S)-Boc-3-(trifluoromethyl)-β-Homophe-OH?
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To request a sample or a quote for (S)-Boc-3-(trifluoromethyl)-β-Homophe-OH, please contact our sales team through the TSS website or by calling our customer service line. Specify the product name and CAS number (270065-77-5).
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