(S)-(6,6′-Dimethoxybiphenyl-2,2′-diyl)bis[bis(4-methylphenyl)phosphine]
(S)-(6,6′-Dimethoxybiphenyl-2,2′-diyl)bis[bis(4-methylphenyl)phosphine] (CAS: 133545-25-2) is a chiral phosphine ligand with the molecular formula C42H40O2P2 and a molecular weight of 638.71 g/mol. This atropisomeric compound, a derivative of MeOBIPHEP, is predominantly utilised as a key component in asymmetric synthesis. It plays a crucial role as a privileged ligand in catalysing various stereoselective transformations, enabling the efficient production of chiral molecules.
- IUPAC
- (S)-2,2′-Bis(di-p-tolylphosphino)-6,6′-dimethoxy-1,1′-biphenyl,(S)-p-Tol-MeOBIPHEP,SL-A102-2
- Synonyms
- 133545-25-2C42H40O2P2(S)-p-Tol-MeOBIPHEPSL-A102-2(S)-2,2′-Bis(di-p-tolylphosphino)-6,6′-dimethoxy-1,1′-biphenyl
![(S)-(6,6′-Dimethoxybiphenyl-2,2′-diyl)bis[bis(4-methylphenyl)phosphine] (C42H40O2P2) — chemical structure, CAS 133545-25-2; Chemistry, fine chemical supplied by Tech Serve Solutions](/_next/image?url=https%3A%2F%2Fpub-f4d920c906024441a773a96f7098e551.r2.dev%2Fimages%2Fproducts%2F133545-25-2.png&w=3840&q=75)
Asymmetric Catalysis
This compound functions as a chiral ligand in transition metal catalysis, facilitating enantioselective reactions crucial for synthesising optically pure compounds.
Synthesis of Pharmaceuticals
Its application in asymmetric synthesis makes it valuable for the production of chiral intermediates and active pharmaceutical ingredients (APIs) where specific stereochemistry is essential.
Advanced Chemical Synthesis
As a privileged ligand, it is employed in complex chemical syntheses requiring high stereocontrol and selectivity, contributing to the development of novel chemical entities.
| Molecular weight | 638.71 |
|---|---|
| Empirical formula | C42H40O2P2 |
| Assay | ≥97% |
| Optical purity | ee: ≥99% |
| Application | Atropisomeric MeOBIPHEP ligands |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (S)-(6,6′-Dimethoxybiphenyl-2,2′-diyl)bis[bis(4-methylphenyl)phosphine] used for?
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This compound is primarily used as a chiral ligand in asymmetric catalysis, enabling stereoselective transformations for the synthesis of chiral molecules, particularly in pharmaceutical and fine chemical production.
What are the CAS number and formula for this compound?
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The CAS number is 133545-25-2, and the molecular formula is C42H40O2P2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this chemical with an assay of ≥97% and optical purity of ee: ≥99%. This is a research-grade chemical and is not supplied as USP, BP, EP, or any other pharmacopoeia grade.
What are the safety and handling considerations for this chemical?
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This compound requires appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter is recommended. It carries a WGK Germany rating of 3, indicating it is hazardous to water.
How is this chemical typically packed and shipped?
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Tech Serve Solutions exports chemicals globally, ensuring secure and compliant packaging suitable for international transport. Specific packing details can be provided upon request.
How can I request a sample or quote?
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To request a sample or a quotation for (S)-(6,6′-Dimethoxybiphenyl-2,2′-diyl)bis[bis(4-methylphenyl)phosphine], please contact our sales team through the website or by calling our office.
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