(S)-(–)-5-(2-Pyrrolidinyl)-1H-tetrazole
(S)-(–)-5-(2-Pyrrolidinyl)-1H-tetrazole (CAS: 33878-70-5; Formula: C5H9N5) is a proline-derived organocatalyst supplied by Tech Serve Solutions. With a molecular weight of 139.16 g/mol, this chiral compound is primarily utilized in asymmetric synthesis. It serves as an effective catalyst for reactions leading to the formation of complex heterocyclic structures, particularly in the synthesis of dihydropyridazines and 1,2-oxazines.
- IUPAC
- (S)-(–)-2-Tetrazol-5-ylpyrrolidine,Proline Tetrazole Catalyst
- Synonyms
- (S)-(–)-2-Tetrazol-5-ylpyrrolidineProline Tetrazole Catalyst
Asymmetric Synthesis of Dihydropyridazines
This compound acts as an organocatalyst in the asymmetric synthesis of dihydropyridazines. Its chiral nature allows for the enantioselective formation of these important heterocyclic structures, crucial in various chemical syntheses.
Synthesis of 1,2-Oxazines
It is employed as a catalyst in the asymmetric synthesis of 1,2-oxazines. This application leverages its chiral properties to achieve high stereoselectivity in the formation of the oxazine ring system.
Chiral Catalyst
As a chiral catalyst, (S)-(–)-5-(2-Pyrrolidinyl)-1H-tetrazole is valuable in stereoselective organic transformations. It is part of the broader class of proline-based organocatalysts used to control the stereochemical outcome of reactions.
| Molecular weight | 139.16 |
|---|---|
| Empirical formula | C5H9N5 |
| Assay | 96% |
| Optical activity | [α]20/D -9.0°, c = 1 in methanol |
| Application | Organocatalyst used for asymmetric synthesis of dihydropyridazines and 1,2-oxazines.8,9 |
| Melting point | 253-258 °C |
Hazard statements
- H301Toxic if swallowed
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P301IF SWALLOWED
- P305IF IN EYES
| Protective equipment | Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges |
|---|---|
| Transport (UN / ADR) | UN 2811 6.1 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | T |
| Risk statements (R) | 25-36/37/38 |
| Safety statements (S) | 26-36/37-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (S)-(–)-5-(2-Pyrrolidinyl)-1H-tetrazole used for?
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This compound is used as an organocatalyst in asymmetric synthesis, particularly for the preparation of dihydropyridazines and 1,2-oxazines.
What is the CAS number and formula for (S)-(–)-5-(2-Pyrrolidinyl)-1H-tetrazole?
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The CAS number is 33878-70-5, and the empirical formula is C5H9N5.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this chemical with an assay of 96%. We do not represent this product as USP, BP, or EP grade.
How should (S)-(–)-5-(2-Pyrrolidinyl)-1H-tetrazole be handled?
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This compound is classified as Danger with hazards including H301 (Toxic if swallowed), H315 (Causes skin irritation), H319 (Causes serious eye irritation), and H335 (May cause respiratory irritation). Always use appropriate personal protective equipment, including eyeshields, face shields, gloves, and a P2 respirator.
Is (S)-(–)-5-(2-Pyrrolidinyl)-1H-tetrazole a controlled substance?
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The provided data does not indicate that this compound is a controlled substance.
How is this chemical shipped and exported by TSS?
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Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, handling all aspects of international shipping and export documentation in compliance with regulations.
How can I request a sample or quote for (S)-(–)-5-(2-Pyrrolidinyl)-1H-tetrazole?
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Please contact our sales team directly through the website to request a sample or obtain a quotation for this product.
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