(S)-(+)-5-(Trityloxymethyl)-2-pyrrolidinone
(S)-(+)-5-(Trityloxymethyl)-2-pyrrolidinone (CAS: 105526-85-0; Formula: C24H23NO2; Molar Mass: 357.44) is a chiral pyrrolidinone derivative. This compound serves as a valuable building block in asymmetric synthesis, notably in Diels-Alder reactions and conjugate additions. Its enantiopure nature makes it crucial for stereoselective chemical transformations, facilitating the synthesis of complex organic molecules.
Asymmetric Diels-Alder Reactions
This chiral pyrrolidinone derivative is employed as a key intermediate in enantioselective Diels-Alder cycloadditions, enabling the construction of complex cyclic structures with controlled stereochemistry.
Asymmetric Conjugate Additions
It finds application in asymmetric Michael additions and related conjugate addition reactions, providing a stereodirecting influence for the formation of new carbon-carbon bonds.
Chiral Building Block
As a versatile chiral building block, it facilitates the synthesis of enantiomerically enriched pharmaceutical intermediates and fine chemicals.
| Molecular weight | 357.44 |
|---|---|
| Empirical formula | C24H23NO2 |
| Assay | 98% |
| Optical activity | [α]20/D +15°, c = 1 in chloroform |
| Application | Used in asymmetric Diels-Alder reactions1 and asymmetric conjugate additions.2 |
| Melting point | 164-166 °C(lit.) |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-37/39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (S)-(+)-5-(Trityloxymethyl)-2-pyrrolidinone used for?
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(S)-(+)-5-(Trityloxymethyl)-2-pyrrolidinone is primarily used in asymmetric synthesis, including asymmetric Diels-Alder reactions and asymmetric conjugate additions. It serves as a chiral building block for creating enantiomerically enriched molecules.
What are the CAS number and formula for (S)-(+)-5-(Trityloxymethyl)-2-pyrrolidinone?
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The CAS number is 105526-85-0, and the empirical formula is C24H23NO2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies (S)-(+)-5-(Trityloxymethyl)-2-pyrrolidinone with an assay of 98%. This product is not represented as USP, BP, or EP grade.
What are the safety considerations when handling this chemical?
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This compound is a Warning material, classified with H315 (causes skin irritation), H319 (causes serious eye irritation), and H335 (may cause respiratory irritation). Appropriate personal protective equipment, including a dust mask (type N95), eyeshields, and gloves, should be used. Ensure adequate ventilation. Store in a cool, dry place away from incompatible materials.
Is this product available for export?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals. (S)-(+)-5-(Trityloxymethyl)-2-pyrrolidinone can be packed and shipped internationally.
How can I request a sample or quote?
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To request a sample or a quotation for (S)-(+)-5-(Trityloxymethyl)-2-pyrrolidinone, please contact our sales team through the website or by phone, providing your specific requirements.
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