(S)-(+)-5-Oxo-2-tetrahydrofurancarboxylic acid
(S)-(+)-5-Oxo-2-tetrahydrofurancarboxylic acid (CAS: 21461-84-7), with the molecular formula C5H6O4 and a molecular weight of 130.10 g/mol, is a chiral building block. This compound is primarily utilised in asymmetric synthesis and chemical research. Its applications include the preparation of municatacin analogues, which have demonstrated cytotoxic activity against tumour cells, making it a valuable reagent in medicinal chemistry and drug discovery research.
- IUPAC
- (S)-γ-Carboxy-γ-butyrolactone,(S)-5-Oxotetrahydro-2-furancarboxylic acid
- Synonyms
- (S)-γ-Carboxy-γ-butyrolactone(S)-5-Oxotetrahydro-2-furancarboxylic acid
Asymmetric Synthesis
Serves as a chiral building block in asymmetric synthesis, enabling the stereoselective construction of complex molecules. It is valuable for introducing specific chirality into target compounds.
Medicinal Chemistry Research
Utilised in the preparation of potential therapeutic agents, such as municatacin analogues. These analogues have shown cytotoxic activity against tumour cells, highlighting its role in drug discovery.
Organic Synthesis Intermediate
Functions as a versatile intermediate in general organic synthesis. Its functional groups allow for various chemical transformations, contributing to the development of novel chemical entities.
| Molecular weight | 130.10 |
|---|---|
| Empirical formula | C5H6O4 |
| Assay | 98% |
| Boiling point | 150-155 °C/0.2 mmHg(lit.) |
| Optical activity | [α]20/D +14°, c = 5 in methanol |
| Optical purity | ee: 99% (GLC) |
| Application | Used to prepare municatacin analogs which show cytotoxic activity on tumor cells.1 |
| Melting point | 71-73 °C(lit.) |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (S)-(+)-5-Oxo-2-tetrahydrofurancarboxylic acid used for?
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It is used in asymmetric synthesis and for preparing municatacin analogues that exhibit cytotoxic activity on tumour cells, making it valuable in medicinal chemistry and drug discovery.
What is the CAS number and formula for this compound?
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The CAS number is 21461-84-7 and the empirical formula is C5H6O4.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this chemical with an assay of 98%. We do not represent it as USP, BP, or EP grade unless explicitly stated in the product data.
How should (S)-(+)-5-Oxo-2-tetrahydrofurancarboxylic acid be handled safely?
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Handle with appropriate personal protective equipment including a dust mask (N95 US type), eyeshields, and gloves. Avoid breathing dust, ensure good ventilation, and wash hands thoroughly after handling. It is classified as a Warning substance with hazards H315, H319, and H335.
How is this chemical packed, shipped, and exported?
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This chemical is carefully packed according to industry standards to ensure safe transit and is available for global export by Tech Serve Solutions.
How can I request a sample or quote for (S)-(+)-5-Oxo-2-tetrahydrofurancarboxylic acid?
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Please contact our sales team directly through our website or by phone to request a sample or a formal quotation for your specific needs.
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