S-(2-Thiazolyl)-L-cysteine
S-(2-Thiazolyl)-L-cysteine (CAS: 405150-20-1), a chiral unnatural amino acid derivative with the molecular formula C6H8N2O2S2 and a molecular weight of 204.27 g/mol, is supplied by Tech Serve Solutions. This compound finds utility in chemical biology and synthesis, particularly within peptide chemistry and as a cysteine derivative. Its stereospecific enzymatic synthesis ensures high optical purity.
- IUPAC
- (R)-2-Amino-3-(2-thiazolylthio)propionic acid

Peptide Synthesis
S-(2-Thiazolyl)-L-cysteine serves as a valuable building block in the synthesis of modified peptides. Its incorporation can introduce unique structural and functional properties into peptide chains.
Chemical Biology Research
This unnatural amino acid derivative is employed in chemical biology to probe biological systems. Its distinct structure can be used to study protein function, interactions, or to develop novel biochemical tools.
Cysteine Derivative Synthesis
The compound is utilized as a precursor or intermediate in the synthesis of various other cysteine derivatives. These derivatives may have applications in medicinal chemistry or materials science.
Drug Discovery and Development
As an unnatural amino acid, S-(2-Thiazolyl)-L-cysteine can be incorporated into potential therapeutic agents during drug discovery. This may confer improved stability, bioavailability, or target specificity.
| Molecular weight | 204.27 |
|---|---|
| Empirical formula | C6H8N2O2S2 |
| Assay | ≥95.0% (HPLC) |
| Optical purity | ee: >99% (due to stereospecific enzymatic synthesis) |
| Storage temperature | 2-8°C |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is S-(2-Thiazolyl)-L-cysteine used for?
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S-(2-Thiazolyl)-L-cysteine is primarily used in chemical biology and chemical synthesis, including peptide chemistry and as a cysteine derivative. It also finds applications in unnatural amino acid derivative synthesis.
What are the CAS number and molecular formula for S-(2-Thiazolyl)-L-cysteine?
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The CAS number for S-(2-Thiazolyl)-L-cysteine is 405150-20-1, and its molecular formula is C6H8N2O2S2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies S-(2-Thiazolyl)-L-cysteine with an assay of ≥95.0% (HPLC) and high optical purity (ee: >99%). TSS does not represent this product as USP, BP, or EP grade.
How should S-(2-Thiazolyl)-L-cysteine be handled and stored?
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Handling requires appropriate personal protective equipment, including eyeshields, gloves, and a type N95 (US) or type P1 (EN143) respirator filter. The compound should be stored at 2-8°C. It has a WGK Germany rating of 3.
How is S-(2-Thiazolyl)-L-cysteine packed and shipped?
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Tech Serve Solutions professionally packs and ships chemicals globally, adhering to all necessary regulations for safe transport. Specific packing details can be provided upon request.
How can I request a quote or sample for S-(2-Thiazolyl)-L-cysteine?
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To request a quote or sample, please contact our sales department through the website or by phone. Our team will be happy to assist you with your inquiry.
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