S-(1-Oxido-2-pyridyl)-N,N,N′,N′-tetramethylthiuronium tetrafluoroborate
S-(1-Oxido-2-pyridyl)-N,N,N′,N′-tetramethylthiuronium tetrafluoroborate (CAS 255825-38-8) is a versatile organic compound with the molecular formula C10H16BF4N3OS and a molecular weight of 313.12 g/mol. It serves as a key reagent in various chemical synthesis applications, notably in peptide coupling and the preparation of amides. Its utility extends to the synthesis of anticonvulsant drugs and the conversion of carboxylic acids into specific amide derivatives.
- IUPAC
- N,N,N′,N′-Tetramethyl-S-(1-oxido-2-pyridyl)thiuronium tetrafluoroborate,S-(2-Pyridyl)-N,N,N′,N′-tetramethylthiuronium N-oxide tetrafluoroborate
- Synonyms
- N′-tetramethylthiuronium tetrafluoroborate,255825-38-8, C10H16BF4N3OS, N,N,N′,N′-Tetramethyl-S-(1-oxido-2-pyridyl)thiuronium tetrafluoroborate,S-(2-Pyridyl)-N,N,N′,N′-tetramethylthiuronium N-oxide tetrafluoroborate
Peptide Coupling Reagent
This compound is effectively employed in both solution-phase and solid-phase peptide synthesis. It facilitates the formation of peptide bonds with high yields, making it a valuable tool for constructing peptides and peptidomimetics.
Amide Synthesis
It enables the rapid and efficient preparation of primary amides from carboxylic acids. Furthermore, it can be used to convert carboxylic acids into N-methoxy or N-benzoxy amides, including the formation of Weinreb amides.
Anticonvulsant Synthesis
This reagent has been documented for its application in the synthesis pathways leading to anticonvulsant medications, contributing to the development of pharmaceutical agents.
| Molecular weight | 313.12 |
|---|---|
| Empirical formula | C10H16BF4N3OS |
| Assay | ≥95.0% (NMR) |
| Storage temperature | −20°C |
| Application | Reagent for: Synthesis of anticonvulsants1 Solution and solid-phase peptide coupling2,3 Conversion of carboxylic acids to Weinreb amides and N-methoxy or N-benzoxy amides4 Rapid and high-yielding preparation of primary amides5,3 |
| Melting point | 109-114 °C |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is S-(1-Oxido-2-pyridyl)-N,N,N′,N′-tetramethylthiuronium tetrafluoroborate used for?
+
This compound is primarily used as a reagent in peptide coupling, the synthesis of amides (including Weinreb amides), and the preparation of anticonvulsants.
What are the CAS number and molecular formula for this chemical?
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The CAS number is 255825-38-8, and the molecular formula is C10H16BF4N3OS.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this chemical with an assay of ≥95.0% (NMR). It is supplied as a research or technical grade; TSS does not represent it as USP, BP, or EP grade.
How should S-(1-Oxido-2-pyridyl)-N,N,N′,N′-tetramethylthiuronium tetrafluoroborate be handled safely?
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This compound is a Warning irritant (H315, H319, H335). Handle with appropriate personal protective equipment, including eyeshields, gloves, and a dust mask type N95 (US). Avoid breathing dust and ensure good ventilation.
How is this chemical typically shipped and exported?
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This chemical is stored at -20°C and is carefully packaged and exported globally by Tech Serve Solutions to meet international shipping standards.
How can I request a sample or quote?
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To request a sample or obtain a quotation, please contact our sales team through the 'Contact Us' section of our website.
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