(S)-2-Piperazinecarboxylic acid dihydrochloride
(S)-2-Piperazinecarboxylic acid dihydrochloride (CAS: 158663-69-5), with the molecular formula C5H10N2O2 · 2HCl and a molecular weight of 203.07 g/mol, is a vital building block in chemical synthesis. This chiral compound serves as a key intermediate in the preparation of other valuable amino acid derivatives. It is supplied by Tech Serve Solutions with an assay of ≥98.0% (T), suitable for research and development applications in organic chemistry and biochemistry.

Chiral Synthesis Intermediate
Utilised in the preparation of enantiomerically pure piperazine and piperidine carboxylic acids through stereoselective enzymatic resolutions. This is crucial for creating complex chiral molecules.
Peptide Chemistry
Serves as a building block for the incorporation of unnatural amino acid derivatives into peptide chains, enabling the study and development of novel peptidomimetics and modified peptides.
Biochemical Research
Employed in biochemical studies as a modified amino acid derivative, aiding in the investigation of enzyme mechanisms, protein structure, and the development of new biologically active compounds.
| Molecular weight | 203.07 |
|---|---|
| Empirical formula | C5H10N2O2 · 2HCl |
| Assay | ≥98.0% (T) |
| Optical activity | [α]20/D −5±1°, c = 1% in H2O |
| Application | Preparation of (S)-piperazine-2-carboxylic acid, (R)-piperazine-2-carboxylic acid, and (S)-piperidine-2-carboxylic acid by kinetic resolution of the corresponding racemic carboxamides with stereoselective amidases in whole bacterial cells1 |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (S)-2-Piperazinecarboxylic acid dihydrochloride used for?
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It is primarily used as a chiral intermediate in chemical synthesis, particularly for preparing enantiomerically pure piperazine and piperidine carboxylic acids, and in peptide chemistry for creating modified peptides.
What are the CAS number and molecular formula for (S)-2-Piperazinecarboxylic acid dihydrochloride?
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The CAS number is 158663-69-5, and the molecular formula is C5H10N2O2 · 2HCl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies (S)-2-Piperazinecarboxylic acid dihydrochloride with an assay of ≥98.0% (T). This product is intended for research and laboratory use. Tech Serve Solutions does not represent this product as USP, BP, EP, or any other pharmacopoeia grade.
How should (S)-2-Piperazinecarboxylic acid dihydrochloride be handled?
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It is a Warning substance that causes skin irritation, serious eye irritation, and may cause respiratory irritation. Handle with appropriate personal protective equipment, including a dust mask type N95 (US), eyeshields, and gloves. Ensure good ventilation and avoid breathing dust. In case of eye contact, rinse cautiously with water for several minutes and remove contact lenses if present and easy to do. Continue rinsing.
Is (S)-2-Piperazinecarboxylic acid dihydrochloride available for export?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including (S)-2-Piperazinecarboxylic acid dihydrochloride.
How can I request a sample or quote?
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To request a sample or a quote for (S)-2-Piperazinecarboxylic acid dihydrochloride, please contact the Tech Serve Solutions sales team via the website or listed contact details.
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