(S)-(−)-2-(Boc-amino)-3-cyclohexyl-1-propanol
(S)-(−)-2-(Boc-amino)-3-cyclohexyl-1-propanol (CAS: 103322-56-1) is a chiral building block with the linear formula C<sub>6</sub>H<sub>11</sub>CH<sub>2</sub>CH[NHCO<sub>2</sub>C(CH<sub>3</sub>)<sub>3</sub>]CH<sub>2</sub>OH and a molecular weight of 257.37 g/mol. This optically active amino alcohol is primarily utilised as a precursor in asymmetric synthesis, facilitating the creation of complex organic molecules with specific stereochemistry, including the synthesis of alpha-amino aldehydes.
- IUPAC
- (S)-(−)-2-(tert-Butoxycarbonylamino)-3-cyclohexyl-1-propanol
![(S)-(−)-2-(Boc-amino)-3-cyclohexyl-1-propanol (C6H11CH2CH[NHCO2C(CH3)3]CH2OH) — chemical structure, CAS 103322-56-1; Chemistry, fine chemical supplied by Tech Serve Solutions](/_next/image?url=https%3A%2F%2Fpub-f4d920c906024441a773a96f7098e551.r2.dev%2Fimages%2Fproducts%2F103322-56-1.png&w=3840&q=75)
Precursor for Chiral Aldehydes
Serves as a key intermediate in the synthesis of (S)-N-t-Boc-cyclohexylalaninal, an alpha-amino aldehyde. This transformation is achieved through oxidation, yielding the aldehyde with high optical purity.
Asymmetric Synthesis
Valuable building block in asymmetric synthesis due to its defined stereochemistry. It enables the stereoselective construction of complex organic molecules in pharmaceutical and fine chemical research.
Organic Synthesis
Used in general organic synthesis as a functionalised chiral alcohol and protected amine. It provides a convenient starting point for introducing cyclohexylalanine derivatives into target molecules.
| Molecular weight | 257.37 |
|---|---|
| Linear formula | C6H11CH2CH[NHCO2C(CH3)3]CH2OH |
| Assay | 90% |
| Boiling point | 214 °C(lit.) |
| Density | 1.126 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.464(lit.) |
| Optical activity | [α]20/D −25°, c = 1 in ethanol |
| Application | Precursor to (S)-N-t-Boc-cyclohexylalaninal.1 This precursor was oxidized to the corresponding α-amino aldehyde in good yield and high optical purity.2 |
Hazard statements
- H226Flammable liquid and vapour
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | Eyeshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 58 °C / 136.4 °F |
| Transport (UN / ADR) | UN 3272 3 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (S)-(−)-2-(Boc-amino)-3-cyclohexyl-1-propanol used for?
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(S)-(−)-2-(Boc-amino)-3-cyclohexyl-1-propanol is used as a precursor in asymmetric synthesis, particularly for the preparation of chiral alpha-amino aldehydes.
What is the CAS number and formula for (S)-(−)-2-(Boc-amino)-3-cyclohexyl-1-propanol?
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The CAS number is 103322-56-1 and the linear formula is C<sub>6</sub>H<sub>11</sub>CH<sub>2</sub>CH[NHCO<sub>2</sub>C(CH<sub>3</sub>)<sub>3</sub>]CH<sub>2</sub>OH.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this product at a minimum assay of 90%. It is suitable for research and general chemical synthesis. We do not represent this product as USP, BP, EP, or pharmaceutical grade.
How should (S)-(−)-2-(Boc-amino)-3-cyclohexyl-1-propanol be handled safely?
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This compound is flammable and may cause skin, eye, and respiratory irritation. Handle with appropriate personal protective equipment, including safety glasses, gloves, and use in a well-ventilated area or with respiratory protection.
Is this chemical a controlled substance?
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No, this chemical is not listed as a controlled substance.
How is (S)-(−)-2-(Boc-amino)-3-cyclohexyl-1-propanol packed and shipped?
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The product is packed according to industry standards for chemical transportation and is available for export globally. Specific shipping details can be provided upon request.
How can I request a sample or a quote?
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To request a sample or a quotation, please contact our sales team through the website or by phone, providing the product name and CAS number.
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