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(S)-(−)-2-(Boc-amino)-1,4-butanediol

CAS 128427-10-1HOCH2CH2CH[NHCO2C(CH3)3]CH2OHChemical Synthesis

(S)-(−)-2-(Boc-amino)-1,4-butanediol (CAS 128427-10-1) is a chiral building block with the linear formula HOCH2CH2CH[NHCO2C(CH3)3]CH2OH and a molecular weight of 205.25 g/mol. This protected amino alcohol offers valuable stereochemistry for asymmetric synthesis and complex organic molecule construction. Its protected amine and two hydroxyl functionalities make it a versatile intermediate in the development of pharmaceuticals and other fine chemicals where precise stereochemical control is essential.

Synonyms
HOCH2CH2CH[NHCO2C(CH3)3]CH2OH
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(S)-(−)-2-(Boc-amino)-1,4-butanediol (HOCH2CH2CH[NHCO2C(CH3)3]CH2OH) — chemical structure, CAS 128427-10-1; Chemistry, fine chemical supplied by Tech Serve Solutions
Amino AlcoholsAsymmetric SynthesisChemical SynthesisChiral Building BlocksOrganic Building Blocks
01 /Applications

Chiral Synthesis

Utilised as a stereochemically defined building block in asymmetric synthesis. Its chiral centre and functional groups allow for the construction of complex chiral molecules.

Pharmaceutical Intermediates

Serves as a key intermediate in the synthesis of active pharmaceutical ingredients (APIs). The Boc-protected amine and diol structure are valuable for creating stereospecific drug candidates.

Organic Building Blocks

Provides a versatile scaffold for various organic transformations. The presence of two primary alcohol groups and a protected amine enables diverse derivatisation pathways.

02 /Properties
Molecular weight205.25
Linear formulaHOCH2CH2CH[NHCO2C(CH3)3]CH2OH
Assay97%
Optical activity[α]20/D −8°, c = 1 in chloroform
Melting point65-69 °C(lit.)
03 /Safety & handling
Protective equipmentEyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Water hazard class (WGK, DE)3

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry
CAS number
128427-10-1
MDL number
MFCD03093946
PubChem substance
24878173
05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is (S)-(−)-2-(Boc-amino)-1,4-butanediol used for?

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(S)-(−)-2-(Boc-amino)-1,4-butanediol is primarily used as a chiral building block in asymmetric synthesis and as an intermediate in the production of pharmaceuticals and fine chemicals where stereochemical control is critical.

What is the CAS number and formula for (S)-(−)-2-(Boc-amino)-1,4-butanediol?

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The CAS number is 128427-10-1 and the linear formula is HOCH2CH2CH[NHCO2C(CH3)3]CH2OH.

What grade and purity does Tech Serve Solutions supply?

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Tech Serve Solutions supplies this product with an assay of 97%. As this is not specified as USP, EP, or BP grade, TSS does not represent it as such and it should be considered for research or technical use.

What are the safety considerations for handling (S)-(−)-2-(Boc-amino)-1,4-butanediol?

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Appropriate personal protective equipment, including eyeshields and gloves, should be used. In environments with potential for airborne dust or aerosols, a P1 (EN143) or N95 (US) respirator filter is recommended. Its WGK is 3, indicating it is hazardous to water.

How is this chemical packed, shipped, and exported?

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Tech Serve Solutions, established in 1998, is a specialist global supplier and exporter of fine chemicals. Products are carefully packed according to international shipping regulations and exported worldwide.

How can I request a sample or quote for (S)-(−)-2-(Boc-amino)-1,4-butanediol?

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To request a sample or quote, please contact our sales team through the website or by phone, providing your details and the product CAS number 128427-10-1.

Need (S)-(−)-2-(Boc-amino)-1,4-butanediol in a specific grade or volume?