(S)-2-Azido-3-tert-butoxypropionic acid cyclohexylammonium salt
(S)-2-Azido-3-tert-butoxypropionic acid cyclohexylammonium salt (CAS: 1228077-87-9) is a specialized organic compound with the molecular formula C7H13N3O3 ·C6H13N and a molecular weight of 286.37. This chiral azido-amino acid derivative serves as a valuable building block in organic synthesis. Its structure makes it particularly useful in asymmetric synthesis and peptide chemistry, enabling the introduction of azido functionalities in complex molecular architectures.
- IUPAC
- L-Azidoserine tert-butyl ether cyclohexylammonium salt,N3-Ser(OtBu)-OH CHA salt
- Synonyms
- L-Azidoserine tert-butyl ether cyclohexylammonium saltN3-Ser(OtBu)-OH CHA salt

Asymmetric Synthesis
This chiral compound is employed as a building block in asymmetric synthesis, allowing for the stereoselective construction of complex molecules. Its defined stereochemistry is critical for creating enantiomerically pure products.
Peptide Chemistry
It functions as a valuable reagent in peptide synthesis, enabling the incorporation of azido-modified amino acids into peptide chains. This can be used for further functionalization or in the development of peptidomimetics.
Organic Synthesis Intermediate
The presence of both an azide and a protected amino acid moiety makes it a versatile intermediate for various organic transformations. It can be used to access a range of nitrogen-containing compounds.
Chemical Biology Research
As an amino acid derivative with an azide group, it can be utilized in chemical biology for bioconjugation strategies, click chemistry reactions, or for probing biological pathways.
| Molecular weight | 286.37 |
|---|---|
| Empirical formula | C7H13N3O3 ·C6H13N |
| Assay | ≥98% (TLC) |
| Optical activity | [α]/D +3.7±0.3°, c = 1 in methanol |
| Storage temperature | 2-8°C |
| Composition | carbon, 54.0-55.0%nitrogen, 19.1-19.9% |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (S)-2-Azido-3-tert-butoxypropionic acid cyclohexylammonium salt used for?
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This compound is primarily used as a chiral building block in asymmetric synthesis, in peptide chemistry for incorporating azido-amino acids, as a versatile intermediate in organic synthesis, and in chemical biology research for bioconjugation and probing biological pathways.
What are the CAS number and molecular formula?
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The CAS number is 1228077-87-9, and the molecular formula is C7H13N3O3 ·C6H13N.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this chemical with an assay of ≥98% (TLC). We do not represent this product as USP, BP, EP, or any pharmacopoeia grade.
How should (S)-2-Azido-3-tert-butoxypropionic acid cyclohexylammonium salt be handled?
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This compound is classified as a Warning and can cause skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335). It is recommended to use a dust mask type N95 (US), eyeshields, and gloves during handling. Ensure good ventilation and avoid breathing dust.
How is this product shipped and exported by TSS?
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Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals. We handle the packing and export of this product, ensuring compliance with international shipping regulations.
How can I request a quote or sample?
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To request a quote or a sample, please contact our sales department through the website or by calling our direct line. Our team will be happy to assist you with your requirements.
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