(S)-(−)-1-(4-Bromophenyl)ethylamine
(S)-(−)-1-(4-Bromophenyl)ethylamine (CAS: 27298-97-1; C8H10BrN) is a chiral amine of significant value in organic synthesis. With a molecular weight of 200.08 g/mol, this compound is primarily utilised as a chiral building block and resolving agent. Its specific stereochemistry makes it crucial for the asymmetric synthesis of complex molecules, particularly in the pharmaceutical and agrochemical industries.
- IUPAC
- (S)-(−)-4-Bromo-α-methylbenzylamine
- Synonyms
- (S)-(−)-4-Bromo-α-methylbenzylamine
Chiral Building Block
This enantiomerically pure amine serves as a fundamental component in the construction of more complex chiral molecules. Its defined stereocenter allows for the introduction of chirality in a controlled manner, essential for producing stereospecific drugs and other biologically active compounds.
Chiral Resolving Agent
Its chiral nature makes it an effective agent for the separation of racemic mixtures. By forming diastereomeric salts with chiral acids, it facilitates the resolution and isolation of individual enantiomers.
Intermediate in Pharmaceutical Synthesis
It is used as a key intermediate in the synthesis pathways for various pharmaceutical active ingredients (APIs). The incorporation of its chiral moiety is often critical for the efficacy and safety of the final drug product.
Asymmetric Synthesis
The compound is employed in various asymmetric synthesis strategies to create enantiomerically enriched products. Its specific structure and chirality are leveraged in catalytic and stoichiometric processes.
| Molecular weight | 200.08 |
|---|---|
| Empirical formula | C8H10BrN |
| Assay | ≥98.0% (sum of enantiomers, GC) |
| Density | 1.390 g/mL at 20 °C(lit.) |
| Refractive index | n20/D 1.567 |
| Optical activity | [α]20/D −20.5±1°, c = 3% in methanol |
Hazard statements
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Transport (UN / ADR) | UN 2735 8/PG 3 |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 34 |
| Safety statements (S) | 26-28-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (S)-(−)-1-(4-Bromophenyl)ethylamine used for?
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This compound is primarily used as a chiral building block and a chiral resolving agent in organic synthesis, particularly for the asymmetric synthesis of pharmaceuticals and other complex organic molecules.
What are the CAS number and formula for (S)-(−)-1-(4-Bromophenyl)ethylamine?
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The CAS number is 27298-97-1, and the empirical formula is C8H10BrN.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies (S)-(−)-1-(4-Bromophenyl)ethylamine with an assay of ≥98.0% (sum of enantiomers, GC). We do not represent this product as USP, BP, or EP grade.
How should (S)-(−)-1-(4-Bromophenyl)ethylamine be handled safely?
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This substance causes severe skin burns and eye damage (H314). Handling requires appropriate personal protective equipment, including gloves, goggles, a face shield, and a suitable respirator. In case of contact, immediate and thorough rinsing is essential, followed by medical attention. Refer to the Safety Data Sheet for full handling instructions.
Is (S)-(−)-1-(4-Bromophenyl)ethylamine a controlled substance?
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Based on the provided data, there is no indication that (S)-(−)-1-(4-Bromophenyl)ethylamine is a controlled substance. However, customers should verify local regulations.
How is (S)-(−)-1-(4-Bromophenyl)ethylamine packed, shipped, and exported?
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This product is shipped as UN 2735, Class 8, Packing Group III. Packaging adheres to international transport regulations for hazardous materials. Tech Serve Solutions is experienced in global export.
How can I request a quote or sample?
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To request a quote or a sample, please contact our sales department via the website or direct email, providing your specific requirements and delivery details.
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