(S)-(−)-1-Amino-2-(methoxymethyl)pyrrolidine
(S)-(−)-1-Amino-2-(methoxymethyl)pyrrolidine (CAS: 59983-39-0; Formula: C6H14N2O; MW: 130.19) is a chiral heterocyclic compound utilized primarily as a building block in asymmetric synthesis. Its enantiomerically pure structure makes it valuable for constructing complex chiral molecules. This versatile pyrrolidine derivative is a key intermediate in the synthesis of various organic compounds, particularly in the pharmaceutical and fine chemical industries.
- IUPAC
- SAMP
Asymmetric Synthesis
This compound serves as a chiral auxiliary or building block in enantioselective synthesis. Its defined stereochemistry allows for the creation of specific enantiomers of target molecules, which is crucial in pharmaceutical development.
Pharmaceutical Intermediates
It is employed in the multi-step synthesis of active pharmaceutical ingredients (APIs). The pyrrolidine ring and chiral centre are often incorporated into drug structures for enhanced biological activity.
Chiral Ligand Development
The amino and ether functionalities make it a potential precursor for the development of chiral ligands used in asymmetric catalysis, enabling selective chemical transformations.
Research and Development
Utilised in academic and industrial research labs for exploring novel synthetic routes and developing new chemical entities with specific stereochemical properties.
| Molecular weight | 130.19 |
|---|---|
| Empirical formula | C6H14N2O |
| Assay | 95% |
| Boiling point | 42 °C/1.8 mmHg(lit.) |
| Density | 0.97 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.465(lit.) |
| Optical activity | [α]20/D −79°, neat |
| Optical purity | ee: 97% (GLC) |
| Protective equipment | Eyeshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 72 °C / 161.6 °F |
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (S)-(−)-1-Amino-2-(methoxymethyl)pyrrolidine used for?
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(S)-(−)-1-Amino-2-(methoxymethyl)pyrrolidine is primarily used as a chiral building block in asymmetric synthesis and as an intermediate in the preparation of pharmaceuticals and other complex organic molecules.
What are the CAS number and formula for (S)-(−)-1-Amino-2-(methoxymethyl)pyrrolidine?
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The CAS number is 59983-39-0, and the empirical formula is C6H14N2O.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies (S)-(−)-1-Amino-2-(methoxymethyl)pyrrolidine with an assay of 95% and an optical purity of ee: 97% (GLC). It is supplied as a research chemical and is not represented as USP, BP, or EP grade.
What are the safety considerations for handling this chemical?
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This compound is flammable with a flash point of 72 °C (161.6 °F). Appropriate personal protective equipment, including eyeshields, gloves, and a suitable respirator, should be used. Refer to the Safety Data Sheet for comprehensive handling guidelines.
How is this chemical packed and shipped by TSS?
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Tech Serve Solutions packs and ships chemicals according to international regulations, ensuring safe transit. Please contact us for specific details regarding export procedures for your region.
How can I request a sample or quote for (S)-(−)-1-Amino-2-(methoxymethyl)pyrrolidine?
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To request a sample or a quote, please use the 'Request Quote' or 'Sample Request' form on our website, or contact our sales team directly via email or phone.
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