(S)-(+)-1-(2-Pyrrolidinylmethyl)pyrrolidine
(S)-(+)-1-(2-Pyrrolidinylmethyl)pyrrolidine (CAS 51207-66-0), with the molecular formula C9H18N2 and a molecular weight of 154.25 g/mol, is a chiral amine extensively utilised in asymmetric synthesis. It serves as a valuable building block and ligand in various catalytic processes, facilitating the enantioselective formation of complex organic molecules. This compound is a key reagent for chemists seeking precise stereochemical control in synthetic pathways.
Chiral Ligand in Asymmetric Catalysis
This compound functions as a chiral ligand in metal-catalyzed asymmetric reactions. Its structure enables the induction of enantioselectivity, leading to the preferential formation of one stereoisomer over another in organic transformations.
Organocatalysis
As a proline-derived amine, it can act as an organocatalyst in various asymmetric reactions. This catalytic activity is crucial for reactions requiring high enantiomeric purity without the need for metal catalysts.
Synthetic Building Block
The molecule's diamine structure and chirality make it a versatile building block for the synthesis of more complex chiral molecules, including pharmaceuticals and fine chemicals.
| Molecular weight | 154.25 |
|---|---|
| Empirical formula | C9H18N2 |
| Assay | 96% |
| Boiling point | 99-101 °C/2 mmHg(lit.) |
| Density | 0.946 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.4871(lit.) |
| Optical activity | [α]19/D +7.0°, c = 2.4 in ethanol |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | Eyeshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 88 °C / 190.4 °F |
| Transport (UN / ADR) | NA 1993 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (S)-(+)-1-(2-Pyrrolidinylmethyl)pyrrolidine used for?
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(S)-(+)-1-(2-Pyrrolidinylmethyl)pyrrolidine is primarily used as a chiral ligand in asymmetric catalysis and as an organocatalyst in various enantioselective synthetic transformations. It also serves as a versatile chiral building block in organic synthesis.
What are the CAS number and formula for (S)-(+)-1-(2-Pyrrolidinylmethyl)pyrrolidine?
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The CAS number is 51207-66-0 and the empirical formula is C9H18N2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies (S)-(+)-1-(2-Pyrrolidinylmethyl)pyrrolidine with an assay of 96%. TSS does not represent this product as USP, BP, EP, or any other pharmacopoeia grade; it is suitable for research and chemical synthesis applications.
How should (S)-(+)-1-(2-Pyrrolidinylmethyl)pyrrolidine be handled?
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Handle with appropriate personal protective equipment, including eyeshields and gloves. Ensure adequate ventilation, as this compound can cause skin irritation (H315), serious eye irritation (H319), and respiratory irritation (H335).
Is (S)-(+)-1-(2-Pyrrolidinylmethyl)pyrrolidine shipped internationally?
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Yes, Tech Serve Solutions, as a specialist global supplier and exporter, exports (S)-(+)-1-(2-Pyrrolidinylmethyl)pyrrolidine worldwide.
How can I request a sample or quote?
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To request a sample or a quote for (S)-(+)-1-(2-Pyrrolidinylmethyl)pyrrolidine, please contact the Tech Serve Solutions sales team through our website or by phone.
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