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(S)-(+)-1-Amino-2-propanol

CAS 2799-17-9CH3CH(OH)CH2NH2Chemical Synthesis

(S)-(+)-1-Amino-2-propanol (CAS: 2799-17-9), a chiral amino alcohol with the formula CH3CH(OH)CH2NH2 and a molecular weight of 75.11 g/mol, serves as a valuable building block in asymmetric synthesis. Its distinct stereochemistry makes it crucial for creating enantiomerically pure compounds. This chemical finds application in the synthesis of complex organic molecules, particularly in pharmaceutical research and development where precise stereochemical control is paramount.

IUPAC
(+)-Isopropanolamine
Synonyms
(+)-Isopropanolamine(S)-2-Aminopropan-1-ol(S)-1-Amino-2-hydroxypropane
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(S)-(+)-1-Amino-2-propanol (CH3CH(OH)CH2NH2) — chemical structure, CAS 2799-17-9; Chemistry, fine chemical supplied by Tech Serve Solutions
Amino AlcoholsAsymmetric SynthesisChemical SynthesisChiral Building BlocksChiral Resolution ReagentsChiral Resolving Reagents
01 /Applications

Chiral Building Block in Organic Synthesis

Utilised as a key chiral synthon for constructing enantiomerically pure molecules. Its stereogenic centre is essential for introducing specific chirality into target compounds, particularly in complex multi-step syntheses.

Pharmaceutical Intermediate

Serves as an intermediate in the synthesis of active pharmaceutical ingredients (APIs) where stereochemical purity is critical. Its amino and hydroxyl groups offer versatile reaction sites for further functionalization.

Chiral Resolving Agent

Can be employed in the resolution of racemic mixtures, enabling the separation of enantiomers. This is vital for obtaining chirally pure compounds required for specific biological activities.

Ligand Synthesis

Used in the preparation of chiral ligands for asymmetric catalysis. These ligands play a crucial role in directing stereoselective reactions, enhancing efficiency and enantioselectivity in chemical transformations.

02 /Properties
Molecular weight75.11
Linear formulaCH3CH(OH)CH2NH2
Assay98%
Boiling point160 °C(lit.)
Density0.954 g/mL at 25 °C(lit.)
Refractive indexn20/D 1.4437(lit.)
Optical activity[α]20/D +18°, c = 1.8 in H2O
Melting point24-26 °C(lit.)
Vapour pressure<1 mmHg (20 °C)
Vapour density2.6 (vs air)
03 /Safety & handling
GHS hazard pictogram: Corrosive (GHS05)
Corrosive
Danger

Hazard statements

  • H314Causes severe skin burns and eye damage

Precautionary statements

  • P280Wear protective gloves, clothing and eye/face protection
  • P305IF IN EYES
  • P310Immediately call a POISON CENTER or doctor
Protective equipmentFaceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter
Flash point71 °C / 159.8 °F
Transport (UN / ADR)UN 3259PSN1 8 / PGII
Water hazard class (WGK, DE)3
Hazard codes (EU)C
Risk statements (R)34
Safety statements (S)23-26-36-45

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry
CAS number
2799-17-9
MDL number
MFCD00064429
PubChem substance
24854349
Beilstein registry
1718868
05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is (S)-(+)-1-Amino-2-propanol used for?

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(S)-(+)-1-Amino-2-propanol is primarily used as a chiral building block in organic synthesis, particularly for pharmaceutical intermediates and in asymmetric catalysis. It is also employed as a chiral resolving agent.

What is the CAS number and formula for (S)-(+)-1-Amino-2-propanol?

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The CAS number is 2799-17-9 and the linear formula is CH3CH(OH)CH2NH2.

What grade and purity does Tech Serve Solutions supply?

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Tech Serve Solutions supplies (S)-(+)-1-Amino-2-propanol with an assay of 98%. We do not represent this product as USP, BP, or EP grade.

What are the main safety hazards associated with (S)-(+)-1-Amino-2-propanol?

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(S)-(+)-1-Amino-2-propanol is classified as Danger, with hazard statement H314 indicating it causes severe skin burns and eye damage. Appropriate personal protective equipment, including faceshields, gloves, and suitable respirators, must be used when handling.

How is (S)-(+)-1-Amino-2-propanol packed, shipped, and exported?

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This chemical is packed according to international shipping regulations for hazardous materials. Tech Serve Solutions is a global supplier and exporter, experienced in safely shipping chemicals worldwide.

How can I request a quote or sample for (S)-(+)-1-Amino-2-propanol?

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To request a quote or a sample, please contact our sales team via the details provided on our website, specifying the product CAS number 2799-17-9.

Need (S)-(+)-1-Amino-2-propanol in a specific grade or volume?