Ruthenium Red
Ruthenium Red (CAS 11103-72-3) is a specialized organometallic compound with the linear formula [(NH₃)₅RuORu(NH₃)₄ORu(NH₃)₅]Cl₆. It is a complex salt of ruthenium, appearing as a dark red solid. This compound is primarily recognized for its biological activity, serving as an inhibitor of the mitochondrial Ca²⁺ uniporter and acting as a vanilloid receptor antagonist. Its molecular weight is 786.35 g/mol.
- IUPAC
- Ammoniated ruthenium oxychloride
- Synonyms
- Ammoniated ruthenium oxychloride
![Ruthenium Red ([(NH3)5RuORu(NH3)4ORu(NH3)5]Cl6) — chemical structure, CAS 11103-72-3; Life Science, fine chemical supplied by Tech Serve Solutions](/_next/image?url=https%3A%2F%2Fpub-f4d920c906024441a773a96f7098e551.r2.dev%2Fimages%2Fproducts%2F11103-72-3.png&w=3840&q=75)
Mitochondrial Calcium Uniporter Inhibition
Ruthenium Red is a potent inhibitor of the mitochondrial calcium uniporter (MCU), a key protein complex responsible for calcium uptake into mitochondria. This makes it a valuable tool for studying mitochondrial calcium homeostasis and its role in cellular processes.
Vanilloid Receptor Antagonism
This compound acts as an antagonist for VR1 vanilloid receptors, which are ion channels involved in pain and temperature sensation. Its ability to block these channels makes it useful in research focused on neuroscience and pain pathways.
Cell Biology Research
As a bioactive small molecule, Ruthenium Red is employed in various cell biology studies to investigate cellular signaling, calcium flux, and the function of ion channels within different cell types.
Histology and Staining
Ruthenium Red is also known for its use as a stain in histology and cytology. It can selectively stain certain cellular components, aiding in microscopic examination and analysis.
| Molecular weight | 786.35 |
|---|---|
| Linear formula | [(NH3)5RuORu(NH3)4ORu(NH3)5]Cl6 |
| Assay | ≥85% (calc. on dry substance, AT) |
| Impurities tested | ~5% water |
| Application | Inhibits mitochondrial Ca2+ uniporter; capsaicin antagonist; blocks VR1 vanilloid receptor-coupled ion channels. |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Colour Index Number | 77800 |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Ruthenium Red used for?
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Ruthenium Red is primarily used in research as an inhibitor of the mitochondrial Ca²⁺ uniporter and as a vanilloid receptor antagonist. It also finds application as a histological stain.
What are the CAS number and formula for Ruthenium Red?
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The CAS number for Ruthenium Red is 11103-72-3, and its linear formula is [(NH₃)₅RuORu(NH₃)₄ORu(NH₃)₅]Cl₆.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Ruthenium Red with an assay of ≥85% (calculated on dry substance, AT). It contains approximately 5% water and is not represented as USP, BP, or EP grade.
What are the safety and handling considerations for Ruthenium Red?
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Ruthenium Red is classified with WGK Germany 3. Appropriate personal protective equipment, including eyeshields, gloves, and a type N95 (US) or type P1 (EN143) respirator filter, should be used when handling this compound.
How is Ruthenium Red packed, shipped, and exported?
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Tech Serve Solutions carefully packs and prepares Ruthenium Red for safe shipping and global export, adhering to all relevant regulations for chemical transport.
How can I request a sample or quote for Ruthenium Red?
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To request a sample or a quote for Ruthenium Red, please contact the Tech Serve Solutions sales team through our website or direct inquiry channels.
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